{"id":16433,"date":"2025-01-16T13:36:27","date_gmt":"2025-01-16T13:36:27","guid":{"rendered":"https:\/\/www.globalresearchdata.kr\/?p=4311"},"modified":"2026-09-06T22:22:04","modified_gmt":"2026-09-06T13:22:04","slug":"smn1-gene-replacement-market-datam","status":"publish","type":"post","link":"https:\/\/www.globalresearch.co.kr\/insight\/smn1-gene-replacement-market-datam\/","title":{"rendered":"\uc138\uacc4\uc758 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 (2024-2031) : \uc720\ud615\ubcc4 (\uc720\ud615 0 SMA, \uc720\ud615 1 SMA, \uc720\ud615 2 SMA, \uc720\ud615 3 SMA, \uc720\ud615 4 SMA), \uc81c\ud488 \uc720\ud615\ubcc4 (\uc624\ub098\uc148\ub178\uc9c4 \uc544\ubca0\ud30c\ub974\ubcf4\ubca1, \ub204\uc2dc\ub108\uc13c , \ub9ac\uc2a4\ub514\ud50c\ub7a8, \uae30\ud0c0)"},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

    \n
  1. \ubc29\ubc95\ub860 \ubc0f \ubc94\uc704<\/b>\n
      \n
    1. \uc5f0\uad6c \ubc29\ubc95\ub860<\/li>\n
    2. \ubcf4\uace0\uc11c\uc758 \uc5f0\uad6c \ubaa9\uc801 \ubc0f \ubc94\uc704<\/li>\n<\/ol>\n<\/li>\n
    3. \uc815\uc758 \ubc0f \uac1c\uc694<\/b><\/li>\n
    4. \uc784\uc6d0 \uc694\uc57d<\/b>\n
        \n
      1. \uc720\ud615\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      2. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      3. \uc5f0\ub839\ub300\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      4. \uad00\ub9ac \uacbd\ub85c\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      5. \ud310\ub9e4 \ucc44\ub110\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      6. \uc9c0\uc5ed\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n<\/ol>\n<\/li>\n
      7. \uc5ed\ud559<\/b>\n
          \n
        1. \uc601\ud5a5 \uc694\uc778\n
            \n
          1. \ub3d9\uc778\n
              \n
            1. \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \ubc1c\ubcd1\ub960 \uc99d\uac00<\/li>\n
            2. XX<\/li>\n<\/ol>\n<\/li>\n
            3. \uc81c\uc57d\n
                \n
              1. \ub192\uc740 \uce58\ub8cc \ube44\uc6a9<\/li>\n<\/ol>\n<\/li>\n
              2. \uae30\ud68c<\/li>\n
              3. \uc601\ud5a5 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
              4. \uc0b0\uc5c5 \ubd84\uc11d<\/b>\n
                  \n
                1. \ud3ec\ud130\uc758 \ub2e4\uc12f \uac00\uc9c0 \ud798 \ubd84\uc11d<\/li>\n
                2. \uacf5\uae09\ub9dd \ubd84\uc11d<\/li>\n
                3. \uac00\uaca9 \ubd84\uc11d<\/li>\n
                4. \uaddc\uc81c \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n
                5. \uc720\ud615\ubcc4<\/b>\n
                    \n
                  1. \uc18c\uac1c\n
                      \n
                    1. \uc720\ud615\ubcc4 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                    2. \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218, \uc720\ud615\ubcc4<\/li>\n<\/ol>\n<\/li>\n
                    3. \uc720\ud615 0 SMA *\n
                        \n
                      1. \uc18c\uac1c<\/li>\n
                      2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<\/ol>\n<\/li>\n
                      3. \uc720\ud615 1 SMA<\/li>\n
                      4. \uc720\ud615 2 SMA<\/li>\n
                      5. \uc720\ud615 3 SMA<\/li>\n
                      6. \uc720\ud615 4 SMA<\/li>\n<\/ol>\n<\/li>\n
                      7. \uc81c\ud488 \uc720\ud615\ubcc4<\/b>\n
                          \n
                        1. \uc18c\uac1c\n
                            \n
                          1. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                          2. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                          3. \uc624\ub098\uc148\ub178\uc9c4 \uc544\ubca0\ud30c\ub974\ubcf4\ubca1 * *\n
                              \n
                            1. \uc18c\uac1c<\/li>\n
                            2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<\/ol>\n<\/li>\n
                            3. \ub204\uc2dc\ub108\uc13c<\/li>\n
                            4. \ub9ac\uc2a4\ub514\ud50c\ub818<\/li>\n
                            5. \uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n
                            6. \uc5f0\ub839\ub300\ubcc4<\/b>\n
                                \n
                              1. \uc18c\uac1c\n
                                  \n
                                1. \uc5f0\ub839\ub300\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%), \uc5f0\ub839\ub300\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n
                                2. \uc5f0\ub839\ub300\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                                3. \uc18c\uc544\uacfc *\n
                                    \n
                                  1. \uc18c\uac1c<\/li>\n
                                  2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<\/ol>\n<\/li>\n
                                  3. \uc131\uc778<\/li>\n<\/ol>\n<\/li>\n
                                  4. \ud22c\uc5ec \uacbd\ub85c\ubcc4<\/b>\n
                                      \n
                                    1. \uc18c\uac1c\n
                                        \n
                                      1. \ud22c\uc5ec \uacbd\ub85c\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                      2. \ud22c\uc5ec \uacbd\ub85c\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                                      3. \uacbd\uad6c*\n
                                          \n
                                        1. \uc18c\uac1c<\/li>\n
                                        2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<\/ol>\n<\/li>\n
                                        3. Intrathecal<\/li>\n
                                        4. \uc815\ub9e5 \ub0b4<\/li>\n<\/ol>\n<\/li>\n
                                        5. \ud310\ub9e4 \ucc44\ub110\ubcc4<\/b>\n
                                            \n
                                          1. \uc18c\uac1c\n
                                              \n
                                            1. \ud310\ub9e4 \ucc44\ub110\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                            2. \ud310\ub9e4 \ucc44\ub110\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                                            3. \uc720\ud1b5 \ucc44\ub110 *\n
                                                \n
                                              1. \uc18c\uac1c<\/li>\n
                                              2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d (%)<\/li>\n
                                              3. \ubcd1\uc6d0 \uc57d\uad6d<\/li>\n
                                              4. \uc18c\ub9e4 \uc57d\uad6d<\/li>\n
                                              5. \uc628\ub77c\uc778 \uc57d\uad6d<\/li>\n<\/ol>\n<\/li>\n
                                              6. \ucd5c\uc885 \uc0ac\uc6a9\uc790\n
                                                  \n
                                                1. \ubcd1\uc6d0<\/li>\n
                                                2. \uc804\ubb38 \ud074\ub9ac\ub2c9<\/li>\n
                                                3. \uc678\ub798 \uc218\uc220 \uc13c\ud130<\/li>\n
                                                4. \uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                5. \uc9c0\uc5ed\ubcc4<\/b>\n
                                                    \n
                                                  1. \uc18c\uac1c\n
                                                      \n
                                                    1. \uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                    2. \uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                                                    3. \ubd81\ubbf8\n
                                                        \n
                                                      1. \uc18c\uac1c<\/li>\n
                                                      2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                      3. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%), \uc720\ud615\ubcc4<\/li>\n
                                                      4. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                      5. \uc5f0\ub839\ub300 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                      6. \uad00\ub9ac \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                      7. \ud310\ub9e4 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                      8. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                          \n
                                                        1. \ubbf8\uad6d<\/li>\n
                                                        2. Canada<\/li>\n
                                                        3. \uba55\uc2dc\ucf54<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                        4. \uc720\ub7fd\n
                                                            \n
                                                          1. \uc18c\uac1c<\/li>\n
                                                          2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                          3. \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                          4. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d (%)<\/li>\n
                                                          5. \uc5f0\ub839\ub300 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                          6. \uad00\ub9ac \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                          7. \ud310\ub9e4 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                          8. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                              \n
                                                            1. \ub3c5\uc77c<\/li>\n
                                                            2. \uc601\uad6d<\/li>\n
                                                            3. \ud504\ub791\uc2a4<\/li>\n
                                                            4. \uc2a4\ud398\uc778<\/li>\n
                                                            5. \uc774\ud0c8\ub9ac\uc544<\/li>\n
                                                            6. \uae30\ud0c0 \uc720\ub7fd<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                            7. \ub0a8\ubbf8\n
                                                                \n
                                                              1. \uc18c\uac1c<\/li>\n
                                                              2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                              3. \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                              4. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                              5. \uc5f0\ub839\ub300 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                              6. \uad00\ub9ac \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                              7. \ud310\ub9e4 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                              8. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                                  \n
                                                                1. \ube0c\ub77c\uc9c8<\/li>\n
                                                                2. \uc544\ub974\ud5e8\ud2f0\ub098<\/li>\n
                                                                3. \ub098\uba38\uc9c0 \ub0a8\ubbf8<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                                4. \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591\n
                                                                    \n
                                                                  1. \uc18c\uac1c<\/li>\n
                                                                  2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                                  3. \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                                  4. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d (%)<\/li>\n
                                                                  5. \uc5f0\ub839\ub300 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                                  6. \uad00\ub9ac \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                                  7. \ud310\ub9e4 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                                  8. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                                      \n
                                                                    1. \uc911\uad6d<\/li>\n
                                                                    2. \uc778\ub3c4<\/li>\n
                                                                    3. \uc77c\ubcf8<\/li>\n
                                                                    4. \ub300\ud55c\ubbfc\uad6d<\/li>\n
                                                                    5. \uae30\ud0c0 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                                    6. \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74\n
                                                                        \n
                                                                      1. \uc18c\uac1c<\/li>\n
                                                                      2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                                      3. \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                                      4. \uc81c\ud488 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d (%)<\/li>\n
                                                                      5. \uc5f0\ub839\ub300 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                                      6. \uad00\ub9ac \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                                      7. \ud310\ub9e4 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                                      8. \uacbd\uc7c1 \ud658\uacbd<\/b>\n
                                                                          \n
                                                                        1. \uacbd\uc7c1 \uc2dc\ub098\ub9ac\uc624<\/li>\n
                                                                        2. \uc2dc\uc7a5 \ud3ec\uc9c0\uc154\ub2dd\/\uc810\uc720\uc728 \ubd84\uc11d<\/li>\n
                                                                        3. \uc778\uc218\ud569\ubcd1 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n
                                                                        4. \uae30\uc5c5 \ud504\ub85c\ud544<\/b><\/li>\n<\/ol>\n

                                                                           <\/p>\n

                                                                          \"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

                                                                          \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc740 2023\ub144\uc5d0 12\uc5b5 1,000\ub9cc \ub2ec\ub7ec\uc5d0 \ub2ec\ud588\uc73c\uba70 2024-2031\ub144 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 4.9%\uc758 \uc5f0\ud3c9\uade0 \uc131\uc7a5\ub960\ub85c \uc131\uc7a5\ud558\uc5ec 2031\ub144\uc5d0\ub294 17\uc5b5 6,000\ub9cc \ub2ec\ub7ec\uc5d0 \ub2ec\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc740 \uc0dd\uc874 \uc6b4\ub3d9 \ub274\ub7f0-1(SMN1) \uc720\uc804\uc790\uc758 \uae30\ub2a5 \uc0c1\uc2e4 \ub3cc\uc5f0\ubcc0\uc774\ub85c \uc778\ud574 \ubc1c\uc0dd\ud558\ub294 \ud76c\uadc0 \uc720\uc804\uc131 \uc2e0\uacbd\uadfc\uc721 \uc9c8\ud658\uc73c\ub85c, SMN \ub2e8\ubc31\uc9c8 \uacb0\ud54d\uc73c\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4. SMN \ub2e8\ubc31\uc9c8\uc740 \uadfc\uc721\uc758 \uc6c0\uc9c1\uc784\uc744 \uc870\uc808\ud558\ub294 \uc6b4\ub3d9 \ub274\ub7f0\uc758 \uc0dd\uc874\uacfc \uae30\ub2a5\uc5d0 \ud544\uc218\uc801\uc774\uae30 \ub54c\ubb38\uc5d0 \uc774 \ub2e8\ubc31\uc9c8 \uacb0\ud54d\uc740 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4.
                                                                          \nSMA \uc99d\uc0c1\uc758 \uc2ec\uac01\uc131\uc740 SMN1\uacfc \uc720\uc0ac\ud558\uc9c0\ub9cc \uae30\ub2a5\uc801\uc778 SMN \ub2e8\ubc31\uc9c8\uc744 \ud6e8\uc52c \uc801\uac8c \uc0dd\uc131\ud558\ub294 SMN2 \uc720\uc804\uc790\uc758 \uc0ac\ubcf8 \uc218\uc640 \ubc18\ube44\ub840\ud569\ub2c8\ub2e4. SMA\ub294 \uc5fc\uc0c9\uccb4\uc5d0 \uc704\uce58\ud55c SMN1 \uc720\uc804\uc790\uc758 \ub3cc\uc5f0\ubcc0\uc774\ub85c \uc778\ud574 \ubc1c\uc0dd\ud569\ub2c8\ub2e4. SMN2 \uc720\uc804\uc790\uc758 \uc0ac\ubcf8\uc774 \ud558\ub098 \uc774\uc0c1 \uc874\uc7ac\ud558\uba74 \uc9c8\ubcd1\uc758 \uc911\uc99d\ub3c4\uac00 \ub2ec\ub77c\uc9c8 \uc218 \uc788\uc73c\uba70, SMN2 \uc0ac\ubcf8\uc774 \ub9ce\uc740 \uc0ac\ub78c\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uacbd\ubbf8\ud55c \ud615\ud0dc\uc758 SMA\ub97c \uc553\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc774 \ud655\ub300\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

                                                                          \uc2dc\uc7a5 \uc5ed\ud559: \ub3d9\uc778 \ubc0f \uc81c\uc57d \uc694\uc778
                                                                          \n\ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \ubc1c\ubcd1\ub960 \uc99d\uac00
                                                                          \n\ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc758 \ubc1c\ubcd1\ub960 \uc99d\uac00\ub294 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc131\uc7a5\uc744 \ud06c\uac8c \uacac\uc778\ud558\uace0 \uc788\uc73c\uba70, \uc2dc\uc7a5 \uc608\uce21 \uae30\uac04 \ub0b4\ub0b4 \uacac\uc778\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc740 \ud76c\uadc0 \uc720\uc804\uc131 \uc2e0\uacbd\uadfc\uc721 \uc9c8\ud658\uc73c\ub85c \uc601\uc544 \uc0ac\ub9dd\ub960\uc758 \uc8fc\uc694 \uc720\uc804\uc801 \uc6d0\uc778\uc785\ub2c8\ub2e4. \uc774\ub294 \uae30\ub2a5\uc801\uc778 SMN1 \uc720\uc804\uc790\uc758 \ubd80\uc7ac\ub85c \uc778\ud574 \ubc1c\uc0dd\ud558\uba70, \uc6b4\ub3d9 \ub274\ub7f0\uc774 \ube60\ub974\uace0 \ube44\uac00\uc5ed\uc801\uc73c\ub85c \uc190\uc2e4\ub418\uc5b4 \ud638\ud761, \uc0bc\ud0a4\uae30, \uae30\ubcf8 \uc6b4\ub3d9\uacfc \uac19\uc740 \ud544\uc218 \uadfc\uc721 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. SMA\uc758 \uc911\uc99d\ub3c4\ub294 \uc720\ud615\uc5d0 \ub530\ub77c \ub2e4\ub974\uba70, \uc774\ub294 \uc874\uc7ac\ud558\ub294 \ubc31\uc5c5 SMN2 \uc720\uc804\uc790\uc758 \uc0ac\ubcf8 \uc218\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4.
                                                                          \n2022\ub144 1\uc6d4 NCBI \uc5f0\uad6c \ubc1c\ud45c\uc5d0 \ub530\ub974\uba74 \uadfc\uc704\ubd80 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc740 \uac00\uc7a5 \ud754\ud558\uac8c \uc720\uc804\ub418\ub294 \uc720\uc804 \uc9c8\ud658 \uc911 \ud558\ub098\ub85c, \uc720\ubcd1\ub960\uc740 \ucd9c\uc0dd\uc544 11,000\uba85 \uc911 \uc57d 1\uba85, \ubcf4\uc778\uc790 \ube48\ub3c4\ub294 40\uba85 \uc911 1\uba85\uc5d0\uc11c 60\uba85 \uc911 1\uba85\uc5d0 \uc774\ub985\ub2c8\ub2e4. \uc774\ucc98\ub7fc SMA\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc774 \ucee4\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc774 \uc9c8\ud658\uc740 \uc8fc\ub85c \ucc99\uc218\uc758 \uc55e\ucabd \ubfd4\uc5d0 \uc704\uce58\ud55c \uc54c\ud30c \uc6b4\ub3d9 \ub274\ub7f0\uc758 \ud1f4\ud654\ub97c \ud2b9\uc9d5\uc73c\ub85c \ud569\ub2c8\ub2e4. \uac00\uc7a5 \uc2ec\uac01\ud55c \ud615\ud0dc\uc758 SMA\ub294 \uc0dd\ud6c4 6\uac1c\uc6d4 \uc774\uc804\uc5d0 \uc601\uc544\uc5d0\uac8c \ub098\ud0c0\ub098\uba70 \uadfc\ub825 \uc57d\ud654, \uad6c\uadfc \uae30\ub2a5 \uc0c1\uc2e4 \ubc0f \uae30\ud0c0 \uc2ec\uac01\ud55c \uc6b4\ub3d9 \uc7a5\uc560\ub97c \ucd08\ub798\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubaa8\ub4e0 \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc774 \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c, \uc720\uc804\uc790 \uce58\ub8cc\uc758 \ubc1c\uc804\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc774 \ud655\ub300\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub192\uc740 \uce58\ub8cc \ube44\uc6a9
                                                                          \n\ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \uc720\uc804\uc790 \uce58\ub8cc\uc758 \ub192\uc740 \uce58\ub8cc \ube44\uc6a9\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc0c1\ub2f9\ud55c \uc7a5\ubcbd\uc73c\ub85c \uc791\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ube44\uc6a9\uc740 \uac1c\ubcc4 \ud658\uc790\uc5d0\uac8c\ub9cc \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \uc758\ub8cc \uc2dc\uc2a4\ud15c\uacfc \ubcf4\ud5d8 \uc81c\uacf5\uc790\uc5d0\uac8c\ub3c4 \uad11\ubc94\uc704\ud55c \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4.
                                                                          \n2023\ub144 3\uc6d4\uc5d0 \ubc1c\ud45c\ub41c NCBI \uc5f0\uad6c \ub17c\ubb38\uc5d0 \ub530\ub974\uba74, \uc878\uac90\uc2a4\ub9c8(\uc131\ubd84\uba85: \uc624\ub098\uc148\ub178\uc9c4 \uc544\ubca0\ud30c\ubcf4\ubca1)\uc640 \ub204\uc2dc\ub108\uc13c(\uc2a4\ud540\ub77c\uc790)\uc740 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uac00\uc7a5 \ube44\uc2fc \uce58\ub8cc\uc81c\ub85c, \ud658\uc790\uc758 \uc77c\uc0dd \ub3d9\uc548 \ud22c\uc5ec\ub2f9 \ube44\uc6a9\uc774 \uc878\uac90\uc2a4\ub9c8\ub294 \uc57d 420\ub9cc \ub2ec\ub7ec, \ub204\uc2dc\ub108\uc13c\uc740 \uc57d 600\ub9cc \ub2ec\ub7ec\ub85c \ucd94\uc815\ub429\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc640 \uac19\uc740 \uc694\uc778\ub4e4\uc774 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uc81c\ud55c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc2dc\uc7a5 \uc138\ubd84\ud654 \ubd84\uc11d
                                                                          \n\uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc740 \uc720\ud615, \uc81c\ud488 \uc720\ud615, \uc5f0\ub839\ub300, \ud22c\uc5ec \uacbd\ub85c, \ud310\ub9e4 \ucc44\ub110 \ubc0f \uc9c0\uc5ed\uc5d0 \ub530\ub77c \uc138\ubd84\ud654\ub429\ub2c8\ub2e4.
                                                                          \n\uc81c\ud488 \uc720\ud615:
                                                                          \n\uc624\ub098 \uc148 \ub178\uc9c4 \uc544\ubca0 \ud30c\ub974 \ubcf4 \ubca1-xioi \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \uc9c0\ubc30 \ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\uc624\ub098\uc148\ub178\uc9c4 \uc544\ubca0\ud30c\ubcf4\ubca1-XIOI \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc0c1\ub2f9 \ubd80\ubd84\uc744 \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc0c1\ub2f9 \ubd80\ubd84\uc744 \uacc4\uc18d \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\uc878\uac90\uc2a4\ub9c8(\uc624\ub098\uc148\ub178\uc9c4 \uc544\ubca0\ud30c\ubcf4\ubca1)\ub294 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc758 \uc720\uc804\uc801 \uc6d0\uc778\uc744 \uc9c1\uc811 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc720\uc77c\ud55c \uc2b9\uc778 \uc720\uc804\uc790 \uce58\ub8cc\uc81c\ub85c, \uc9c8\ubcd1\uc758 \uc720\uc804\uc801 \uc6d0\uc778\uc744 \uc9c1\uc811 \ud45c\uc801\uc73c\ub85c \ud569\ub2c8\ub2e4. \uc774 \uce58\ub8cc\uc81c\ub294 \uacb0\uc190\ub418\uac70\ub098 \uae30\ub2a5\uc774 \uc5c6\ub294 SMN1 \uc720\uc804\uc790\ub97c \ub300\uccb4\ud558\ub294 \ubc29\uc2dd\uc73c\ub85c \uc791\ub3d9\ud558\uba70, \ud55c \ubc88\uc758 \uc815\ub9e5 \uc8fc\uc785 \ud6c4 SMN \ub2e8\ubc31\uc9c8\uc758 \uc9c0\uc18d\uc801\uc778 \ubc1c\ud604\uc744 \ud1b5\ud574 \uc9c8\ubcd1\uc758 \uc9c4\ud589\uc744 \ub9c9\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc758 \uc694\uc778\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c \uc5c5\uacc4\uc758 \uc8fc\uc694 \uc5c5\uccb4\ub4e4\uc740 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c\uc774 \ubd80\ubb38\uc744 \ucd94\uc9c4\ud560 \uc218\uc788\ub294 \uc5f0\uad6c \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8\uc758 \uc99d\uac00\uc5d0 \ub354 \uc9d1\uc911\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2024\ub144 3\uc6d4 \ub178\ubc14\ud2f0\uc2a4 \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 \ud604\uc7ac \uc878\uac90\uc2a4\ub9c8\ub294 51\uac1c\uad6d \uc774\uc0c1\uc5d0\uc11c \uc2b9\uc778\uc744 \ubc1b\uc558\uc73c\uba70 \uc784\uc0c1\uc2dc\ud5d8 \ubc0f \uad00\ub9ac \uc811\uadfc \ud504\ub85c\uadf8\ub7a8 \ud658\uc790\ub97c \ud3ec\ud568\ud558\uc5ec \uc804 \uc138\uacc4\uc801\uc73c\ub85c 3,700\uba85 \uc774\uc0c1\uc758 \ud658\uc790\uac00 \uce58\ub8cc\ub97c \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub178\ubc14\ud2f0\uc2a4\ub294 SMA\uc5d0 \uac78\ub9b0 \uc5b4\ub9b0\uc774\ub4e4\uc758 \uc0b6\uc744 \uac1c\uc120\ud558\uae30 \uc704\ud574 \ucd5c\uc120\uc744 \ub2e4\ud558\uace0 \uc788\uc73c\uba70, \uad11\ubc94\uc704\ud55c \uc784\uc0c1 \uac1c\ubc1c \ud504\ub85c\uadf8\ub7a8\uc744 \ud1b5\ud574 \uc878\uac90\uc2a4\ub9c8\uc758 \ucd94\uac00 \uc801\uc6a9\uc744 \uc801\uadf9\uc801\uc73c\ub85c \ubaa8\uc0c9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc5ec\uae30\uc5d0\ub294 \ud6c4\uae30 \ubc1c\ubcd1 \ud615\ud0dc\uc758 SMA \ud658\uc790\uc5d0 \ub300\ud55c OAV101\uc758 \ucc99\uc218\uac15 \ub0b4 \ud22c\uc5ec \uac00\ub2a5\uc131\uc744 \uc870\uc0ac\ud558\ub294 \uac83\ub3c4 \ud3ec\ud568\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc694\uc778\ub4e4\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc774 \ubd80\ubb38\uc758 \uc785\uc9c0\ub97c \uacf5\uace0\ud788 \ud588\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub204\uc2dc\ub108\uc13c \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4\uc81c \uc2dc\uc7a5 \uc810\uc720\uc728\uc5d0\uc11c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \ubd80\ubb38\uc785\ub2c8\ub2e4.
                                                                          \n\ub204\uc2dc\ub108\uc13c \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc5d0\uc11c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \ubd80\ubb38\uc774\uba70 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \uc720\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\uc2a4\ud540\ub77c\uc790(\ub204\uc2dc\ub108\uc13c)\ub294 \uccb4\ub0b4 \uc804\uc7a5 \uc0dd\uc874 \uc6b4\ub3d9 \ub274\ub7f0(SMN) \ub2e8\ubc31\uc9c8\uc758 \uc0dd\uc0b0\uc744 \uc9c0\uc18d\uc801\uc73c\ub85c \uc99d\uac00\uc2dc\ucf1c \uc6b4\ub3d9 \ub274\ub7f0 \uc190\uc2e4\uc758 \uadfc\ubcf8 \uc6d0\uc778\uc744 \ud574\uacb0\ud558\ub3c4\ub85d \uc124\uacc4\ub41c \uc548\ud2f0\uc13c\uc2a4 \uc62c\ub9ac\uace0\ub274\ud074\ub808\uc624\ud2f0\ub4dc(ASO)\uc785\ub2c8\ub2e4. \uc6b4\ub3d9 \uc2e0\uacbd\uc138\ud3ec\uac00 \uc788\ub294 \uc911\ucd94 \uc2e0\uacbd\uacc4\uc5d0 \uc9c1\uc811 \ud22c\uc5ec\ud558\uc5ec \uc9c8\ubcd1\uc758 \uadfc\uc6d0\uc744 \ud45c\uc801\uc73c\ub85c \uce58\ub8cc\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c \uc5c5\uacc4\uc758 \uc8fc\uc694 \uc5c5\uccb4\ub4e4\uc740 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c\uc774 \ubd80\ubb38\uc744 \ucd94\uc9c4\ud560 \uc5f0\uad6c \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8\uc758 \uc99d\uac00\uc5d0 \ub354 \uc9d1\uc911\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2024\ub144 9\uc6d4 \ubc14\uc774\uc624\uc820 \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 \uc2a4\ud540\ub77c\uc790(\ub204\uc2dc\ub108\uc13c)\ub294 71\uac1c\uad6d \uc774\uc0c1\uc5d0\uc11c \uc601\uc720\uc544, \uc5b4\ub9b0\uc774 \ubc0f \uc131\uc778\uc758 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \uce58\ub8cc\uc81c\ub85c \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc804 \uc138\uacc4\uc801\uc73c\ub85c 14,000\uba85 \uc774\uc0c1\uc774 \uc2a4\ud540\ub77c\uc790\ub97c \uae30\ucd08 \uce58\ub8cc\uc81c\ub85c \ud22c\uc5ec\ubc1b\uc558\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc640 \uac19\uc740 \uc694\uc778\ub4e4\uc774 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uacac\uc778\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc774 \uce58\ub8cc\ubc95\uc740 \ucd5c\ub300 10\ub144\uac04 \uce58\ub8cc\ubc1b\uc740 \ud658\uc790 \ub370\uc774\ud130\ub97c \ud1b5\ud574 \uc798 \ud655\ub9bd\ub41c \uc548\uc804\uc131 \ud504\ub85c\ud30c\uc77c\uc744 \ubc14\ud0d5\uc73c\ub85c \ub2e4\uc591\ud55c \uc5f0\ub839\uacfc SMA \uc720\ud615\uc5d0 \uac78\uccd0 \uc9c0\uc18d\uc801\uc778 \ud6a8\ub2a5\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4. \ub204\uc2dc\ub108\uc13c\uc758 \uc784\uc0c1 \uac1c\ubc1c \ud504\ub85c\uadf8\ub7a8\uc5d0\ub294 \ub450 \uac1c\uc758 \uc911\ucd94\uc801\uc778 \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8(ENDEAR \ubc0f CHERISH)\uc744 \ud3ec\ud568\ud558\uc5ec \ub2e4\uc591\ud55c \ud658\uc790 \uc9d1\ub2e8\uc5d0\uc11c 460\uba85 \uc774\uc0c1\uc758 \ucc38\uac00\uc790\uac00 \ucc38\uc5ec\ud55c 10\uac74 \uc774\uc0c1\uc758 \uc784\uc0c1 \uc5f0\uad6c\uac00 \ud3ec\ud568\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc9c4\ud589 \uc911\uc778 NURTURE \uc624\ud508 \ub77c\ubca8 \uc5f0\uc7a5 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc2a4\ud540\ub77c\uc790\uc758 \uc7a5\uae30\uc801\uc778 \ud6a8\uacfc\ub97c \ud3c9\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc694\uc778\ub4e4\uc740 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4\uc81c \uc2dc\uc7a5\uc5d0\uc11c \uc774 \ubd80\ubb38\uc758 \uc785\uc9c0\ub97c \uacf5\uace0\ud788 \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc720\ud615
                                                                          \n1\ud615 SMA \ubd80\ubb38\uc774 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4\uc81c \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \uc9c0\ubc30\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n1\ud615 SMA \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \ub300\ubd80\ubd84\uc744 \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc0c1\ub2f9 \ubd80\ubd84\uc744 \uacc4\uc18d \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\ubca0\ub974\ub4dc\ub2c8\ud788-\ud638\ud504\ub9cc\ubcd1 \ub610\ub294 \uc601\uc544\uae30 \ubc1c\ubcd1 SMA\ub85c\ub3c4 \uc54c\ub824\uc9c4 1\ud615 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc740 \uc774 \uc720\uc804 \uc9c8\ud658\uc758 \uac00\uc7a5 \ud754\ud558\uace0 \uc2ec\uac01\ud55c \ud615\ud0dc\uc785\ub2c8\ub2e4. \uc8fc\ub85c \uc601\uc544\uc5d0\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\uba70, \uc77c\ubc18\uc801\uc73c\ub85c \ucd9c\uc0dd \uc2dc \ub610\ub294 \uc0dd\ud6c4 6\uac1c\uc6d4 \uc774\ub0b4\uc5d0 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub0a9\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c \uc5c5\uacc4\uc758 \uc8fc\uc694 \uc5c5\uccb4\ub4e4\uc740 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc774 \ubd80\ubb38\uc744 \ucd94\uc9c4\ud560 \uc5f0\uad6c \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8\uc758 \uc99d\uac00\uc5d0 \ub354\uc6b1 \uc9d1\uc911\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2024\ub144 3\uc6d4 \ub178\ubc14\ud2f0\uc2a4 AG\uc5d0 \ub530\ub974\uba74, SMN2 \uc720\uc804\uc790\ub97c 2\uac1c \ubcf4\uc720\ud55c \ud658\uc790\uc758 \ub300\ubd80\ubd84\uc740 \uac00\uc7a5 \ud754\ud55c \ud615\ud0dc\uc778 1\ud615 SMA\ub85c \ubc1c\ubcd1\ud558\uba70, \uc774\ub294 \uc57d 60%\ub97c \ucc28\uc9c0\ud569\ub2c8\ub2e4. 1\ud615\uc740 \uce58\ub8cc\ud558\uc9c0 \uc54a\uc73c\uba74 \ud2b9\ud788 \uc911\uc99d\uc73c\ub85c \uc9c4\ud589\ub418\uba70, \uac10\uc5fc\ub41c \uc601\uc544\uc758 90% \uc774\uc0c1\uc774 2\uc138\uac00 \ub420 \ub54c\uae4c\uc9c0 \uc0ac\ub9dd\ud558\uac70\ub098 \uc601\uad6c\uc801\uc778 \uc778\uacf5\ud638\ud761\uae30\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \ubc18\uba74, SMN2 \uc720\uc804\uc790\uac00 3\uac1c\uc778 \ud658\uc790\uc758 80% \uc774\uc0c1\uc774 2\ud615 SMA\ub85c \ubc1c\uc804\ud558\uba70, \uc774\ub294 \uc57d 30%\uc5d0 \ud574\ub2f9\ud569\ub2c8\ub2e4.
                                                                          \n\uce58\ub8cc\ub97c \ubc1b\uc9c0 \uc54a\uc740 2\ud615 \ud658\uc790\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uac77\uc9c0 \ubabb\ud558\uace0 \ud720\uccb4\uc5b4\uc5d0 \uc758\uc874\ud558\uac8c \ub418\uba70, 30% \uc774\uc0c1\uc740 25\uc138 \uc774\ud6c4\uc5d0\ub3c4 \uc0dd\uc874\ud558\uc9c0 \ubabb\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b4\ub3d9 \uc2e0\uacbd\uc138\ud3ec \uc190\uc2e4\uc740 \ub418\ub3cc\ub9b4 \uc218 \uc5c6\uc73c\ubbc0\ub85c \uc6b4\ub3d9 \uc2e0\uacbd\uc138\ud3ec\uc758 \ud1f4\ud654\uc640 \uc9c8\ubcd1\uc758 \uc9c4\ud589\uc744 \ub9c9\uae30 \uc704\ud574\uc11c\ub294 \uc870\uae30 \uc9c4\ub2e8\uacfc \uc801\uadf9\uc801\uc778 \ubcf4\uc870 \uce58\ub8cc\ub97c \ud3ec\ud568\ud55c \uc2e0\uc18d\ud55c \uce58\ub8cc\uac00 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc774 \ubd80\ubb38\uc758 \uc785\uc9c0\uac00 \ud655\uace0\ud574\uc84c\uc2b5\ub2c8\ub2e4.
                                                                          \n2\ud615 SMA \ubd80\ubb38\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc5d0\uc11c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \ubd80\ubb38\uc785\ub2c8\ub2e4.
                                                                          \n\uc81c 2 \ud615 SMA \uc138\uadf8\uba3c\ud2b8\ub294 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc5d0\uc11c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \uc138\uadf8\uba3c\ud2b8\uc774\uba70 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \uc720\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\uc81c 2\ud615 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc740 \uc911\uac04 \ud615\ud0dc\uc758 \uc9c8\ubcd1\uc73c\ub85c \ubd84\ub958\ub418\uba70, \uc601\ud5a5\uc744 \ubc1b\ub294 \uc5b4\ub9b0\uc774\uc758 \ud2b9\uc815 \ubc1c\ubcd1 \ubc0f \uae30\ub2a5\uc801 \ub2a5\ub825\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud569\ub2c8\ub2e4. 2\ud615 SMA\uc758 \uc99d\uc0c1\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uc0dd\ud6c4 6\uac1c\uc6d4\uc5d0\uc11c 18\uac1c\uc6d4 \uc0ac\uc774\uc5d0 \uc2dc\uc791\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc9c0\uc5f0\ub41c \ubc1c\ubcd1\uc740 \uc720\uc544\uae30\uc5d0 \ud6e8\uc52c \uc77c\ucc0d \ub098\ud0c0\ub098\ub294 \uc81c 1\ud615 SMA\uc640 \uad6c\ubcc4\ub429\ub2c8\ub2e4.
                                                                          \n\uc81c2\ud615 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc744 \uac00\uc9c4 \uc5b4\ub9b0\uc774\ub294 \uc5c9\ub369\uc774\uc640 \ud5c8\ubc85\uc9c0 \ub4f1 \uc2e0\uccb4 \uc911\uc2ec\uc5d0 \uac00\uc7a5 \uac00\uae4c\uc6b4 \uadfc\uc721\uc778 \uadfc\uc704\ubd80 \uadfc\uc721\uc774 \uc57d\ud654\ub418\ub294 \uac83\uc744 \uacbd\ud5d8\ud569\ub2c8\ub2e4. \ub3c5\ub9bd\uc801\uc73c\ub85c \uc549\uc744 \uc218 \uc788\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc9c0\ub9cc, \uc77c\ubc18\uc801\uc73c\ub85c \uc774\ub3d9\uc744 \uc704\ud574 \ub3c4\uc6c0\uc774 \ud544\uc694\ud558\uba70 \ub098\uc774\uac00 \ub4e4\uc5b4\uac10\uc5d0 \ub530\ub77c \ud720\uccb4\uc5b4\uc5d0 \uc758\uc874\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc9c8\ud658\uc740 \uadfc\uc721 \uc57d\ud654, \ud638\ud761 \uae30\ub2a5 \uc7a5\uc560, \uadfc\uc721 \ubd88\uade0\ud615\uc73c\ub85c \uc778\ud55c \ucc99\ucd94 \uce21\ub9cc\uc99d \ub4f1 \ub2e4\uc591\ud55c \uc99d\uc0c1\uc73c\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uc9c8\ubcd1\uc774 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c \ud658\uc790\ub294 \uc0bc\ud0a4\uace0 \ud638\ud761\ud558\ub294 \ub370 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc744 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc758 \uc694\uc778\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c \uc5c5\uacc4\uc758 \uc8fc\uc694 \uc5c5\uccb4\ub4e4\uc740 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c\uc774 \ubd80\ubb38\uc744 \ucd94\uc9c4\ud560 \uc5f0\uad6c \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8\uc758 \uc99d\uac00\uc5d0 \ub354 \uc9d1\uc911\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, 2022 \ub144 3 \uc6d4 NCBI \uc5f0\uad6c \ubc1c\ud45c\uc5d0 \ub530\ub974\uba74 SMN2 \uc804 RNA \uc2a4\ud50c\ub77c\uc774\uc2f1 \uc870\uc808\uc81c \uc778 risdiplam\uc740 \uc804\uc7a5 SMN \ub2e8\ubc31\uc9c8\uc758 \uc0dd\uc0b0\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\ub294\ub370, \uc774\ub294 \uacb0\ud54d\uc774 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d (SMA)\uc758 \ubcd1\ub9ac \uc0dd\ub9ac\ud559\uc5d0 \uae30\uc5ec\ud558\uae30 \ub54c\ubb38\uc5d0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc784\uc0c1 2\/3\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c \ub9ac\uc2a4\ub514\ud50c\ub78c\uc740 SMA 1\ud615 \uc601\uc544\uc640 2~25\uc138 SMA 2\ud615 \ubc0f 3\ud615 \ud658\uc790\ub4e4\uc758 \uc6b4\ub3d9 \uae30\ub2a5\uc744 \ud06c\uac8c \uac1c\uc120\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc774\ub7ec\ud55c \uc694\uc778\uc73c\ub85c \uc778\ud574 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc774 \ubd80\ubb38\uc758 \uae00\ub85c\ubc8c \uc785\uc9c0\uac00 \uacf5\uace0\ud574\uc84c\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc2dc\uc7a5 \uc9c0\ub9ac\uc801 \uc810\uc720\uc728
                                                                          \n\ubd81\ubbf8\ub294 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc810\uc720\uc728\uc5d0\uc11c \uc911\uc694\ud55c \uc704\uce58\ub97c \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\ubd81\ubbf8\ub294 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc0c1\ub2f9\ud55c \uc704\uce58\ub97c \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70 \ub300\ubd80\ubd84\uc758 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\ubd81\ubbf8\uc5d0\uc11c \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc758 \uc720\ubcd1\ub960\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc \uc635\uc158\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc9c8\ud658\uc5d0 \ub300\ud55c \uc778\uc2dd\uc774 \ub192\uc544\uc9c0\uba74\uc11c \ub354 \ub9ce\uc740 \ud658\uc790\uac00 \uc9c4\ub2e8\uc744 \ubc1b\uace0 \uce58\ub8cc\ub97c \ubc1b\uace0 \uc788\uc73c\uba70, \uc774\ub294 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \ud655\ub300\ub97c \ucd09\uc9c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc758 \ucc44\ud0dd\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uc608\uce21 \uae30\uac04 \ub3d9\uc548 SMNI \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc774 \uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d \uce58\ub8cc\ubc95\uc740 \uc774 \uc9c8\ud658\uc5d0\uc11c \ub0ae\uc740 \uc218\uc900\uc73c\ub85c\ub9cc \ubc1c\ud604\ub418\ub294 \uc0dd\uc874 \uc6b4\ub3d9 \ub274\ub7f0(SMN) \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ud504\ub9ac-\uc5e0\uc54c\uc5d4\uc5d0\uc774 \uc811\ud569\uc744 \uc218\uc815\ud558\uc5ec \uc9c8\ubcd1\uc758 \uc138\ud3ec\uc801 \uae30\ucd08\ub97c \ubc29\ud574\ud558\ub3c4\ub85d \uc124\uacc4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub97c \uae30\ubc18\uc73c\ub85c \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc774 \uac1c\ubc1c\ub418\uace0 \uc788\uc5b4 \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud558\uace0 \uc788\uc73c\uba70, \uc774\ub7ec\ud55c \uce58\ub8cc\ubc95\uc758 \ucc44\ud0dd\uc774 \uc99d\uac00\ud558\uc5ec \ub354 \ub098\uc740 \ud658\uc790 \uce58\ub8cc \uacb0\uacfc\ub85c \uc774\uc5b4\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc758 \uc694\uc778\uc740\uc774 \uc9c0\uc5ed\uc5d0\uc11c \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c\uc774 \uc9c0\uc5ed\uc5d0\uc11c\ub294 \uc8fc\uc694 \uc5c5\uccb4\uc758 \uc874\uc7ac, \uc798 \ubc1c\ub2ec \ub41c \uc758\ub8cc \uc778\ud504\ub77c, \uc815\ubd80 \uc774\ub2c8\uc154\ud2f0\ube0c \ubc0f \uaddc\uc81c \uc9c0\uc6d0, \uae30\uc220 \ubc1c\uc804 \ubc0f \ud22c\uc790, \uc81c\ud488 \ucd9c\uc2dc\uac00\uc774 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \ucd09\uc9c4 \ud560 \uac83\uc785\ub2c8\ub2e4.
                                                                          \n\uc608\ub97c \ub4e4\uc5b4, 2023\ub144 12\uc6d4 \uc2dc\uce74\uace0 \uc564 \uc564 \ub85c\ubc84\ud2b8 \ub8e8\ub9ac \uc544\ub3d9\ubcd1\uc6d0\uc758 \uc2a4\ud0e0\ub9ac \ub9cc \uc5b4\ub9b0\uc774 \uc5f0\uad6c\uc18c\uc758 \uc6a9\ucc28\uc624 \ub9c8(Yongchao C. Ma) \ubc15\uc0ac \uc5f0\uad6c\ud300\uc740 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc5d0\uc11c \uc6b4\ub3d9 \uc2e0\uacbd\uc138\ud3ec \ud1f4\ud589\uc744 \uc720\ubc1c\ud558\ub294 \uc0c8\ub85c\uc6b4 \uba54\ucee4\ub2c8\uc998\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ubc1c\uacac\uc740 \uc720\uc804\uc790 \uce58\ub8cc \ubc0f \uae30\ud0c0 \ud604\uc7ac SMA \uce58\ub8cc\ubc95\uc758 \uc911\uc694\ud55c \ud55c\uacc4\ub97c \uadf9\ubcf5\ud560 \uc218 \uc788\ub294 \uc0c8\ub85c\uc6b4 \uce58\ub8cc \ud45c\uc801\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc640 \uac19\uc740 \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uc9c0\ubc30\uc801\uc778 \uc785\uc9c0\ub97c \uacf5\uace0\ud788 \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc740 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uac00\uc7a5 \ube60\ub978 \uc18d\ub3c4\ub85c \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc740 \uc804 \uc138\uacc4 SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uac00\uc7a5 \ube60\ub978 \uc18d\ub3c4\ub85c \uc131\uc7a5\ud558\uace0 \uc788\uc73c\uba70, \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \ub300\ubd80\ubd84\uc744 \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                                          \n\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc5d0\uc11c \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc758 \uc720\ubcd1\ub960\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc\ubc95\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. SMA\uc5d0 \ub300\ud55c \uc778\uc2dd\uc774 \ud655\ub300\ub428\uc5d0 \ub530\ub77c \ub354 \ub9ce\uc740 \ud658\uc790\uac00 \uc9c4\ub2e8 \ubc0f \uce58\ub8cc\ub97c \ubc1b\uace0 \uc788\uc73c\uba70, \uc774\ub294 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc131\uc7a5\uc5d0 \ub354\uc6b1 \uae30\uc5ec\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\uc774 \uc9c0\uc5ed\uc740 \ub9cc\uc131 \uc9c8\ud658\uc758 \ubd80\ub2f4\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uc720\uc804\uc790 \uce58\ub8cc\uc81c \uac1c\ubc1c\uc5d0 \ub300\ud55c \ud22c\uc790\uac00 \uc99d\uac00\ud558\uace0 \uc788\uc73c\uba70, \ud2b9\ud788 SMA\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ud601\uc2e0\uc801\uc778 \uce58\ub8cc \uc635\uc158\uc5d0 \ub300\ud55c \ud544\uc694\uc131\uc774 \ub192\uc544\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc5d0\uc11c \uc720\uc804\uc790 \uce58\ub8cc\uc5d0 \ub300\ud55c \uae0d\uc815\uc801\uc778 \uacb0\uacfc\ub97c \ub3c4\ucd9c\ud558\ub294 \uc784\uc0c1\uc2dc\ud5d8\uc758 \uc218\uac00 \ub208\uc5d0 \ub744\uac8c \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc99d\uac00\ub294 \uc774\ub7ec\ud55c \uce58\ub8cc \uc635\uc158\uc5d0 \ub300\ud55c \uc758\ub8cc\uc9c4\uacfc \ud658\uc790 \uac04\uc758 \uc2e0\ub8b0\ub97c \ub192\uc5ec\uc90d\ub2c8\ub2e4.
                                                                          \n\uc911\uad6d, \uc77c\ubcf8, \ud55c\uad6d\uacfc \uac19\uc740 \uad6d\uac00\uc5d0\uc11c \uc720\uc804\uc790 \uce58\ub8cc\ub97c \uc804\ubb38\uc73c\ub85c \ud558\ub294 \uc218\ub9ce\uc740 \uc0dd\uba85\uacf5\ud559 \uae30\uc5c5\uc774 \ub4f1\uc7a5\ud558\uba74\uc11c \uc2dc\uc7a5 \ub0b4 \ud601\uc2e0\uacfc \uacbd\uc7c1\uc774 \ucd09\uc9c4\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc2e0\uaddc \uc5c5\uccb4\uc758 \uc720\uc785\uc740 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc694\ubc95\uc758 \uac1c\ubc1c\uacfc \uac00\uc6a9\uc131\uc744 \uac00\uc18d\ud654\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc758 \uc694\uc778\uc740\uc774 \uc9c0\uc5ed\uc5d0\uc11c \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uc131\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub610\ud55c\uc774 \uc9c0\uc5ed\uc758 \uc8fc\uc694 \uc5c5\uccb4, \uc815\ubd80 \uc774\ub2c8\uc154\ud2f0\ube0c, \uc5f0\uad6c \uac1c\ubc1c, \uc9c0\uc6d0 \uaddc\uc81c \ud658\uacbd \ubc0f \uc81c\ud488 \ucd9c\uc2dc\uac00\uc774 SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uc8fc\ub3c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, 2024\ub144 9\uc6d4 \ucd94\uac00\uc774\uc81c\uc57d\uc740 \uc77c\ubcf8 \ud6c4\uc0dd\ub178\ub3d9\uc131\uc774 ‘\uc5d0\ube0c\ub9ac\uc2a4\ub514 \ub4dc\ub77c\uc774 \uc2dc\ub7fd 60mg'(\uc77c\ubc18\uba85: \ub9ac\uc2a4\ub514\ud50c\ub78c)\uc5d0 \ub300\ud574 \ub450 \uac00\uc9c0 \uc911\uc694\ud55c \uc5c5\ub370\uc774\ud2b8\ub97c \uc2b9\uc778\ud588\ub2e4\uace0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. \uccab\uc9f8, \uc720\uc804\uc790 \uac80\uc0ac\ub97c \ud1b5\ud574 \ud655\uc778\ub41c \uc99d\uc0c1 \uc804 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \uce58\ub8cc\uc5d0 \ub300\ud55c \uc801\uc751\uc99d\uc774 \ucd94\uac00\ub85c \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub458\uc9f8, \uc0dd\ud6c4 2\uac1c\uc6d4 \ubbf8\ub9cc\uc758 \ud658\uc790\uc5d0\uac8c \uc801\ud569\ud55c \uc0c8\ub85c\uc6b4 \uc81c\ud615\uc774 \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.
                                                                          \n\ub530\ub77c\uc11c \uc704\uc758 \uc694\uc778\uc73c\ub85c \uc778\ud574 \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc5d0\uc11c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \uc9c0\uc5ed\uc73c\ub85c\uc11c\uc758 \uc785\uc9c0\ub97c \uacf5\uace0\ud788\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

                                                                          \uc8fc\uc694 \uac1c\ubc1c
                                                                          \n2024\ub144 9\uc6d4, \ubc14\uc774\uc624\uc820\uc740 \uce58\ub8cc \uacbd\ud5d8\uc774 \uc5c6\uace0 \uc99d\uc0c1\uc774 \uc788\ub294 \uc720\uc544\uc758 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA) \uce58\ub8cc\ub97c \uc704\ud55c \ub204\uc2dc\ub108\uc13c(\uc2a4\ud540\ub77c\uc790)\uc758 \uace0\uc6a9\ub7c9 \uc694\ubc95\uc744 \uc870\uc0ac\ud55c 2\/3\uc0c1 DEVOTE \uc5f0\uad6c\uc758 \uae0d\uc815\uc801\uc778 \ud0d1\ub77c\uc778 \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\ub294 SMA \ud658\uc790\uc758 \uce58\ub8cc \uacb0\uacfc\ub97c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\ub294 \uac1c\uc120\ub41c \ud22c\uc5ec \uc804\ub7b5\uc758 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec \uc8fc\uc5c8\ub2e4\ub294 \uc810\uc5d0\uc11c \uc911\uc694\ud55c \uc758\ubbf8\uac00 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ubcf4\uace0\uc11c\ub97c \uad6c\ub9e4\ud574\uc57c \ud558\ub294 \uc774\uc720
                                                                          \n\uc720\ud615, \uc81c\ud488 \uc720\ud615, \uc5f0\ub839\ub300, \ud22c\uc5ec \uacbd\ub85c, \ud310\ub9e4 \ucc44\ub110 \ubc0f \uc9c0\uc5ed\uc5d0 \ub530\ub77c \uae00\ub85c\ubc8c SMN1 \uc720\uc804\uc790 \uad50\uccb4 \uc2dc\uc7a5\uc744 \uc138\ubd84\ud654\ud558\uace0 \uc8fc\uc694 \uc0c1\uc5c5 \uc790\uc0b0 \ubc0f \ud50c\ub808\uc774\uc5b4\ub97c \uc774\ud574\ud569\ub2c8\ub2e4.
                                                                          \n\ub3d9\ud5a5\uacfc \uacf5\ub3d9 \uac1c\ubc1c\uc744 \ubd84\uc11d\ud558\uc5ec \uc0c1\uc5c5\uc801 \uae30\ud68c\ub97c \ud30c\uc545\ud569\ub2c8\ub2e4.
                                                                          \n\ubaa8\ub4e0 \uc138\uadf8\uba3c\ud2b8\uac00 \ud3ec\ud568\ub41c SMN1 \uc720\uc804\uc790 \ub300\uccb4 \uc2dc\uc7a5\uc758 \uc218\ub9ce\uc740 \ub370\uc774\ud130 \ud3ec\uc778\ud2b8\uac00 \ud3ec\ud568\ub41c \uc5d1\uc140 \ub370\uc774\ud130 \uc2dc\ud2b8.
                                                                          \nPDF \ubcf4\uace0\uc11c\ub294 \ucca0\uc800\ud55c \uc815\uc131\uc801 \uc778\ud130\ubdf0\uc640 \uc2ec\uce35 \uc5f0\uad6c\ub97c \uac70\uce5c \uc885\ud569\uc801\uc778 \ubd84\uc11d\uc73c\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.
                                                                          \n\ubaa8\ub4e0 \uc8fc\uc694 \uc5c5\uccb4\uc758 \uc8fc\uc694 \uc81c\ud488\uc73c\ub85c \uad6c\uc131\ub41c \uc81c\ud488 \ub9e4\ud551\uc774 \uc5d1\uc140\ub85c \uc81c\uacf5\ub429\ub2c8\ub2e4.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-16433","post","type-post","status-publish","format-standard","hentry","category-market-report"],"_links":{"self":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/16433"}],"collection":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/comments?post=16433"}],"version-history":[{"count":0,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/16433\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/media?parent=16433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/categories?post=16433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/tags?post=16433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}