{"id":16806,"date":"2025-02-07T22:47:09","date_gmt":"2025-02-07T22:47:09","guid":{"rendered":"https:\/\/www.globalresearchdata.kr\/?p=5461"},"modified":"2026-09-13T05:48:20","modified_gmt":"2026-09-12T20:48:20","slug":"checkpoint-inhibitor-refractory-cancer-market-datam","status":"publish","type":"post","link":"https:\/\/www.globalresearch.co.kr\/insight\/checkpoint-inhibitor-refractory-cancer-market-datam\/","title":{"rendered":"\uc138\uacc4\uc758 \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5 (2024-2031) : \uba74\uc5ed \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 (PD-1 \uc5b5\uc81c\uc81c, PDL-1 \uc5b5\uc81c\uc81c, CTLA-4 \uc5b5\uc81c\uc81c), \uc9c8\ubcd1 \uc720\ud615\ubcc4 (\uc804\uc774\uc131 \ud751\uc0c9\uc885, \ube44\uc18c \uc138\ud3ec \ud3d0\uc554, \ub450\uacbd\ubd80\uc554, \ud638 \uc9c0\ud0a8 \ub9bc\ud504\uc885, \uae30\ud0c0)"},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

    \n
  1. \ubc29\ubc95\ub860 \ubc0f \ubc94\uc704<\/b>\n
      \n
    1. \uc5f0\uad6c \ubc29\ubc95\ub860<\/li>\n
    2. \ubcf4\uace0\uc11c\uc758 \uc5f0\uad6c \ubaa9\uc801 \ubc0f \ubc94\uc704<\/li>\n<\/ol>\n<\/li>\n
    3. \uc815\uc758 \ubc0f \uac1c\uc694<\/b><\/li>\n
    4. \uc784\uc6d0 \uc694\uc57d<\/b>\n
        \n
      1. \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uac1c\uc694<\/li>\n
      2. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n
      3. \uc9c0\uc5ed\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n<\/ol>\n<\/li>\n
      4. \uc5ed\ud559<\/b>\n
          \n
        1. \uc601\ud5a5 \uc694\uc778\n
            \n
          1. \ub3d9\uc778\n
              \n
            1. \ub2e4\uc591\ud55c \uc801\uc751\uc99d\uc5d0 \ub300\ud55c \ud611\uc5c5 \ubc0f \uaddc\uc81c \uc2b9\uc778 \uc99d\uac00<\/li>\n
            2. \uae30\uc220 \ubc1c\uc804 \ubc0f \uac1c\ubc1c \uc99d\uac00<\/li>\n<\/ol>\n<\/li>\n
            3. \uc81c\uc57d \uc694\uc778\n
                \n
              1. \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc640 \uad00\ub828\ub41c \uc0dd\uba85\uc744 \uc704\ud611\ud558\ub294 \ud569\ubcd1\uc99d<\/li>\n<\/ol>\n<\/li>\n
              2. \uae30\ud68c<\/li>\n
              3. \uc601\ud5a5 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
              4. \uc0b0\uc5c5 \ubd84\uc11d<\/b>\n
                  \n
                1. \ud3ec\ud130\uc758 \ub2e4\uc12f \uac00\uc9c0 \ud798 \ubd84\uc11d<\/li>\n
                2. \uacf5\uae09\ub9dd \ubd84\uc11d<\/li>\n
                3. \uac00\uaca9 \ubd84\uc11d<\/li>\n
                4. \uaddc\uc81c \ubd84\uc11d<\/li>\n
                5. SWOT \ubd84\uc11d<\/li>\n
                6. \ud2b9\ud5c8 \ubd84\uc11d<\/li>\n
                7. \ub7ec\uc2dc\uc544-\uc6b0\ud06c\ub77c\uc774\ub098 \uc804\uc7c1 \uc601\ud5a5 \ubd84\uc11d<\/li>\n
                8. DMI \uc758\uacac<\/li>\n<\/ol>\n<\/li>\n
                9. \ucf54\ub85c\ub09819 \ubd84\uc11d<\/b>\n
                    \n
                  1. \ucf54\ub85c\ub09819 \ubd84\uc11d\n
                      \n
                    1. \ucf54\ub85c\ub098 \uc774\uc804 \uc2dc\ub098\ub9ac\uc624<\/li>\n
                    2. \ucf54\ub85c\ub09819 \uc911 \uc2dc\ub098\ub9ac\uc624<\/li>\n
                    3. \ucf54\ub85c\ub098 \uc774\ud6c4 \uc2dc\ub098\ub9ac\uc624<\/li>\n<\/ol>\n<\/li>\n
                    4. \ucf54\ub85c\ub09819\uc5d0 \ub530\ub978 \uac00\uaca9 \uc5ed\ud559<\/li>\n
                    5. \uc218\uc694-\uacf5\uae09 \uc2a4\ud399\ud2b8\ub7fc<\/li>\n
                    6. \ud32c\ub370\ubbf9 \uae30\uac04 \uc911 \uc2dc\uc7a5\uacfc \uad00\ub828\ub41c \uc815\ubd80 \uc774\ub2c8\uc154\ud2f0\ube0c<\/li>\n
                    7. \uc81c\uc870\uc5c5\uccb4\uc758 \uc804\ub7b5\uc801 \uc774\ub2c8\uc154\ud2f0\ube0c<\/li>\n
                    8. \uacb0\ub860<\/li>\n<\/ol>\n<\/li>\n
                    9. \uba74\uc5ed \uad00\ubb38 \uc5b5\uc81c\uc81c \uc720\ud615\ubcc4<\/b>\n
                        \n
                      1. \uc18c\uac1c\n
                          \n
                        1. \uba74\uc5ed \uad00\ubb38 \uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                        2. \uba74\uc5ed \uad00\ubb38 \uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                        3. PD-1 \uc5b5\uc81c\uc81c*\n
                            \n
                          1. \uc18c\uac1c<\/li>\n
                          2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<\/ol>\n<\/li>\n
                          3. PDL-1 \uc5b5\uc81c\uc81c<\/li>\n
                          4. CTLA-4 \uc5b5\uc81c\uc81c<\/li>\n<\/ol>\n<\/li>\n
                          5. \uc9c8\ubcd1 \uc720\ud615\ubcc4<\/b>\n
                              \n
                            1. \uc18c\uac1c\n
                                \n
                              1. \uc9c8\ud658 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                              2. \uc9c8\ud658 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                              3. \uc804\uc774\uc131 \ud751\uc0c9\uc885*\n
                                  \n
                                1. \uc18c\uac1c<\/li>\n
                                2. \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                3. \uc7ac\uc870\ud569 \uc778\uac04 NGF \uc810\uc548\uc561<\/li>\n
                                4. \ud608\uccad \uc720\ub798 \uc810\uc548\uc81c<\/li>\n<\/ol>\n<\/li>\n
                                5. \ube44\uc18c\uc138\ud3ec \ud3d0\uc554<\/li>\n
                                6. \ub450\uacbd\ubd80\uc554<\/li>\n
                                7. \ud638\uc9c0\ud0a8 \ub9bc\ud504\uc885<\/li>\n
                                8. \uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n
                                9. \uc9c0\uc5ed\ubcc4<\/b>\n
                                    \n
                                  1. \uc18c\uac1c\n
                                      \n
                                    1. \uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                    2. \uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n
                                    3. \ubd81\ubbf8\n
                                        \n
                                      1. \uc18c\uac1c<\/li>\n
                                      2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559\uad00\uacc4<\/li>\n
                                      3. \uba74\uc5ed \uad00\ubb38 \uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                      4. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                      5. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                          \n
                                        1. \ubbf8\uad6d<\/li>\n
                                        2. \uce90\ub098\ub2e4<\/li>\n
                                        3. \uba55\uc2dc\ucf54<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                        4. \uc720\ub7fd\n
                                            \n
                                          1. \uc18c\uac1c<\/li>\n
                                          2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                          3. \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                          4. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                          5. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                              \n
                                            1. \ub3c5\uc77c<\/li>\n
                                            2. \uc601\uad6d<\/li>\n
                                            3. \ud504\ub791\uc2a4<\/li>\n
                                            4. \uc774\ud0c8\ub9ac\uc544<\/li>\n
                                            5. \uc2a4\ud398\uc778<\/li>\n
                                            6. \uae30\ud0c0 \uc720\ub7fd<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                            7. \ub0a8\ubbf8\n
                                                \n
                                              1. \uc18c\uac1c<\/li>\n
                                              2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                              3. \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d(%)<\/li>\n
                                              4. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                              5. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                  \n
                                                1. \ube0c\ub77c\uc9c8<\/li>\n
                                                2. \uc544\ub974\ud5e8\ud2f0\ub098<\/li>\n
                                                3. \ub098\uba38\uc9c0 \ub0a8\ubbf8<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                4. \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591\n
                                                    \n
                                                  1. \uc18c\uac1c<\/li>\n
                                                  2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                  3. \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d(%)<\/li>\n
                                                  4. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n
                                                  5. \uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n
                                                      \n
                                                    1. \uc911\uad6d<\/li>\n
                                                    2. \uc778\ub3c4<\/li>\n
                                                    3. \uc77c\ubcf8<\/li>\n
                                                    4. \ud638\uc8fc<\/li>\n
                                                    5. \uae30\ud0c0 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                    6. \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74\n
                                                        \n
                                                      1. \uc18c\uac1c<\/li>\n
                                                      2. \uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n
                                                      3. \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n
                                                      4. \uc9c8\ubcd1 \uc720\ud615\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
                                                      5. \uacbd\uc7c1 \ud658\uacbd<\/b>\n
                                                          \n
                                                        1. \uacbd\uc7c1 \uc2dc\ub098\ub9ac\uc624<\/li>\n
                                                        2. \uc2dc\uc7a5 \ud3ec\uc9c0\uc154\ub2dd\/\uc810\uc720\uc728 \ubd84\uc11d<\/li>\n
                                                        3. \uc778\uc218\ud569\ubcd1 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n
                                                        4. \uae30\uc5c5 \ud504\ub85c\ud544<\/b><\/li>\n<\/ol>\n

                                                           <\/p>\n

                                                          \"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

                                                          \uae00\ub85c\ubc8c \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751 \uc131 \uc554 \uc2dc\uc7a5\uc740 \uc608\uce21 \uae30\uac04 2023-2030 \ub144 \ub3d9\uc548 \ub192\uc740 CAGR\uc5d0 \ub3c4\ub2ec \ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.
                                                          \n\uae00\ub85c\ubc8c \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc740 \uc218\ub144\uc5d0 \uac78\uccd0 \uc0c1\ub2f9\ud55c \uc131\uc7a5\uacfc \ubcc0\ud654\ub97c \ubaa9\uaca9\ud588\uc73c\uba70, \ub2e4\uc591\ud55c \uc694\uc778\uc774 \uc5ed\ud559\uc5d0 \uc601\ud5a5\uc744 \ubbf8\ucce4\uc2b5\ub2c8\ub2e4. \ubd88\uc751\uc131 \uc554\uc740 \uce58\ub8cc\uc5d0 \uc989\uc2dc \ubc18\uc751\ud558\uc9c0 \uc54a\uac70\ub098 \ucc98\uc74c\uc5d0\ub294 \uce58\ub8cc\uc5d0 \ubc18\uc751\ud558\uc9c0\ub9cc \ub098\uc911\uc5d0 \ub0b4\uc131\uc774 \uc0dd\uae38 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uba74\uc5ed\uacc4\uc758 ‘\ube0c\ub808\uc774\ud06c’\uac00 \ud480\ub9b0 \ud6c4 \uc120\ucc9c \uba74\uc5ed\uacc4\uc758 \uc7a0\uc7ac\uc801\uc778 \ud56d\uc885\uc591 \ud65c\ub3d9\uc5d0 \ub300\ud55c \uc885\uc591\ud559\uc790\ub4e4\uc758 \uad00\uc2ec\uc740 \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc758 \ud56dCTLA-4 \uce58\ub8cc \uc2b9\uc778\uacfc \ud56dPD-1 \uce58\ub8cc\uc5d0 \ub300\ud55c \uace0\ubb34\uc801\uc778 \ucd08\uae30 \uc784\uc0c1 \uacb0\uacfc \ubcf4\uace0\ub85c \ub2e4\uc2dc \ubd88\ubd99\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc554 \uba74\uc5ed \uce58\ub8cc\uc758 \ubc1c\uc804\uc740 CTLA-4\uc640 PD-1\uacfc \uac19\uc740 \uba74\uc5ed \uccb4\ud06c\ud3ec\uc778\ud2b8\uc758 \ubc1c\uacac\uc73c\ub85c \uc778\ud574 \ud655\uc2e4\ud788 \ucd09\uc9c4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 \uac1c\ubc1c\ub3c4\uc0c1\uad6d\uc758 \uc815\ubd80 \ud22c\uc790\uc640 \uc5f0\uad6c\ub294 PDL-1 \uc5b5\uc81c\uc81c\uc640 \uac19\uc740 \uc0c8\ub85c\uc6b4 \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \ucca8\ub2e8 \uae30\uc220\uc758 \ud65c\uc6a9\uc744 \uc9c0\uc18d\uc801\uc73c\ub85c \ucd09\uc9c4\ud558\uace0 \uae00\ub85c\ubc8c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc744 \ud65c\uc131\ud654\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

                                                          \uc2dc\uc7a5 \uc5ed\ud559
                                                          \n\ub2e4\uc591\ud55c \uc801\uc751\uc99d\uc5d0 \ub300\ud55c \ud611\uc5c5 \ubc0f \uaddc\uc81c \uc2b9\uc778 \uc99d\uac00
                                                          \n\uc120\uc9c4\uad6d\uc5d0\uc11c\ub294 \ub192\uc740 \ud22c\uc790, \uc18c\ub4dd \uc218\uc900, \uc778\ud504\ub77c \uac1c\ubc1c\ub85c \uc778\ud574 \uc758\ub8cc \ubd80\ubb38\uc758 \uac1c\uc120\uc774 \ube60\ub974\uac8c \uc774\ub8e8\uc5b4\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uba87\uba87 \uad6d\uac00\uc5d0\uc11c\ub294 \ub09c\uce58\uc131 \uc554 \uce58\ub8cc\ub97c \uc704\ud55c \uc5f0\uad6c \uc99d\uac00\ub85c \uc778\ud574 \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \ud06c\uac8c \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc5ec\ub7ec \uad6d\uac00 \uac04\uc758 \uae30\uc220 \ubc1c\uc804\uc744 \ud1b5\ud55c \ub2e4\uc591\ud55c \ud611\ub825, \uc778\uc218 \ubc0f \ub77c\uc774\uc13c\uc2a4 \uacc4\uc57d\uc740 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uc774\ub044\ub294 \uc911\uc694\ud55c \uc694\uc18c\uac00 \ub420 \uac83\uc785\ub2c8\ub2e4.
                                                          \n2023\ub144 5\uc6d4 8\uc77c, \uc0c1\uc5c5\ud654 \ub2e8\uacc4\uc5d0 \uc788\ub294 \uc0dd\uba85\uacf5\ud559 \uae30\uc5c5 \ubbf8\ub77c\ud2f0 \ud14c\ub77c\ud4e8\ud2f1\uc2a4(Mirati Therapeutics, Inc.)\uc640 \uc9c0\uc5ed\uc0ac\ud68c \uae30\ubc18 \uc784\uc0c1 \uc5f0\uad6c\ub97c \uc218\ud589\ud558\ub294 \uc138\uacc4 \ucd5c\uace0\uc758 \uc885\uc591\ud559 \uc5f0\uad6c \uae30\uad00 \uc911 \ud558\ub098\uc778 \uc0ac\ub77c \uce90\ub17c \uc5f0\uad6c\uc18c(SCRI)\uac00 \uc804\ub7b5\uc801 \ud30c\ud2b8\ub108\uc2ed\uc744 \ub9fa\uc5b4 \uc784\uc0c1 \uc5f0\uad6c \ubaa8\uc9d1 \uad00\ud589\uc758 \ub2e4\uc591\uc131\uc744 \ub192\uc774\ub294 \uac83\uc774 \ubaa9\ud45c\uc785\ub2c8\ub2e4.
                                                          \n\ub610\ud55c 2023\ub144 3\uc6d4 29\uc77c\uc5d0\ub294 \ub9ac\uc81c\ub124\ub860 \ud30c\ub9c8\uc288\ud2f0\uceec\uc2a4(Regeneron Pharmaceuticals, Inc.)\uac00 \ubc31\uae08 \uae30\ubc18 \ud654\ud559\uc694\ubc95\uacfc \ud568\uaed8 \uc9c4\ud589\uc131 \ube44\uc18c\uc138\ud3ec\ud3d0\uc554(NSCLC)\uc744 \uc553\uace0 \uc788\ub294 PD-L1 \ubc1c\ud604\uc728\uc774 1% \ubbf8\ub9cc\uc778 \uace0\ub839\uc790\uc758 \ucd08\uae30 \uce58\ub8cc\ub97c \uc704\ud574 \ub9ac\ube0c\ud0c0\uc694(\uc131\ubd84\uba85 \uc138\ubbf8\ud50c\ub9ac\ub9d9)\ub97c \uc720\ub7fd\uc704\uc6d0\ud68c(EC)\uc5d0\uc11c \uc2b9\uc778\ubc1b\uc558\uc2b5\ub2c8\ub2e4. \ucd5c\uc885 \ud56d\uc554\ud654\ud559\ubc29\uc0ac\uc120\uc694\ubc95\uc744 \ubc1b\uc744 \uc790\uaca9\uc774 \uc5c6\uace0 EGFR, ALK \ub610\ub294 ROS1 \uc774\uc0c1\uc774 \uc5c6\ub294 \uc804\uc774\uc131 \ub610\ub294 \uad6d\uc18c \uc545\uc131 \uc885\uc591 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud569\ub2c8\ub2e4.
                                                          \n\ub610\ud55c \uc82c\ud37c\ub9ac(\uc131\ubd84\uba85: \ub3c4\uc2a4\ud0c0\ub9ac\ub9d9-\uae00\ub9ac)\ub294 2023\ub144 2\uc6d4 10\uc77c \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc73c\ub85c\ubd80\ud130 \uc774\uc804\uc5d0 \ubc31\uae08 \ud568\uc720 \uce58\ub8cc\ub97c \ubc1b\ub294 \ub3c4\uc911 \ub610\ub294 \uc774\ud6c4\uc5d0 \uc5b4\ub5a4 \uc0c1\ud669\uc5d0\uc11c\ub3c4 \uc9c8\ubcd1\uc774 \uc9c4\ud589\ub418\uc5c8\uace0 \uadfc\uce58\uc801 \uc218\uc220\uc774\ub098 \ubc29\uc0ac\uc120 \uce58\ub8cc\uac00 \uc801\ud569\ud558\uc9c0 \uc54a\uc740 \ubd88\uc77c\uce58 \ubcf5\uad6c \uacb0\ud54d(dMMR) \uc7ac\ubc1c\uc131 \ub610\ub294 \uc9c4\ud589\ub41c \uc790\uad81\ub0b4\ub9c9\uc554 \uc131\uc778 \ud658\uc790\uc758 \uce58\ub8cc\uc81c\ub85c \uc2b9\uc778\ubc1b\uc558\uc2b5\ub2c8\ub2e4(\ubbf8\uad6d FDA \uc2b9\uc778 \ud14c\uc2a4\ud2b8\uc5d0\uc11c \ud655\uc778\ub41c \uacbd\uc6b0).
                                                          \n\ub610\ud55c, \uc554\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uc758\uc57d\ud488\uacfc \uc194\ub8e8\uc158\uc758 \ud65c\uc6a9\ub3c4\uac00 \ub192\uc544\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud601\uc2e0\uc801\uc778 \uc81c\ud488 \uac1c\ubc1c\uc744 \uc704\ud55c \uc5f0\uad6c\uc640 \ud568\uaed8 \ube44\uc18c\uc138\ud3ec\ud3d0\uc554 \uc0ac\ub840\uc758 \uc99d\uac00\uc640 \ud654\ud559\uc694\ubc95 \uc808\ucc28\uc758 \uc99d\uac00\ub294 \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ub09c\uce58\uc131 \uc554 \uc2dc\uc7a5\uc758 \uc131\uc7a5\uc744 \uc774\ub044\ub294 \uc8fc\uc694 \uc694\uc778\uc774 \ub420 \uac83\uc785\ub2c8\ub2e4.
                                                          \n\uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc640 \uad00\ub828\ub41c \uc0dd\uba85\uc744 \uc704\ud611\ud558\ub294 \ud569\ubcd1\uc99d
                                                          \n\uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\ub294 \uc131\uc778\uc5d0\uc11c \uc720\ub9dd\ud55c \uacb0\uacfc\ub97c \ubcf4\uc600\uc74c\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc18c\uc544\uc5d0 \ub300\ud55c \uc548\uc804\uc131\uc5d0 \ub300\ud55c \uc815\ubcf4\ub294 \ub9ce\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ud658\uc790\uc758 70% \uc774\uc0c1\uc774 \uacbd\uc99d\uc5d0\uc11c \uc911\uc99d CTLA-4 \ucc28\ub2e8\uc5d0 \uc774\ub974\ub294 \uc6a9\ub7c9 \uc758\uc874\uc801 \ubd80\uc791\uc6a9\uc744 \uacbd\ud5d8\ud55c \uac83\uc73c\ub85c \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c 18\uac74\uc758 \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub300\ud55c \uba54\ud0c0 \ubd84\uc11d\uc5d0 \ub530\ub974\uba74 \uace0\uc6a9\ub7c9\uc758 CTLA-4 \uc5b5\uc81c\uc81c\ub97c \ud22c\uc5ec\ubc1b\uc740 \ud658\uc790\ub294 \uce58\ub8cc \uad00\ub828 \uc0ac\ub9dd \uc704\ud5d8\uc774 \ub354 \ub192\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.
                                                          \n\ud53c\ub85c\ub294 \uac00\uc7a5 \ud754\ud55c \ubd80\uc791\uc6a9\uc73c\ub85c PD-1 \uc5b5\uc81c\uc81c \ud22c\uc5ec \ud658\uc790\uc758 16~37%, PD-L1 \uc5b5\uc81c\uc81c \ud22c\uc5ec \ud658\uc790\uc758 12~24%\uc5d0\uc11c \ub098\ud0c0\ub0ac\uc9c0\ub9cc, PD-1\/PD-L1 \ucc28\ub2e8\uacfc \uad00\ub828\ub41c \ub3c5\uc131\uc740 CTLA-4 \uc5b5\uc81c\uc81c\ubcf4\ub2e4 \ub35c \uc2ec\uac01\ud558\uac8c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 \uc911\uc694\ud55c \uc7a5\uae30\uc5d0 \ub300\ud55c \uc608\uae30\uce58 \uc54a\uc740 \ud45c\uc801 \uc774\ud0c8 \ud6a8\uacfc\ub294 \uc7a5\uae30\uac00 \uc544\uc9c1 \ubc1c\ub2ec \uc911\uc778 \uccad\uc18c\ub144\uc758 \uc0dd\uba85\uc744 \uc704\ud5d8\uc5d0 \ube60\ub728\ub9b4 \uc218 \uc788\uc5b4 \uc6b0\ub824\uc2a4\ub7ec\uc6b4 \uc0c1\ud669\uc785\ub2c8\ub2e4.
                                                          \n\uc138\ubd84\ud654 \ubd84\uc11d
                                                          \n\uae00\ub85c\ubc8c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc740 \uba74\uc5ed \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \uc720\ud615, \uc9c8\ubcd1 \uc720\ud615 \ubc0f \uc9c0\uc5ed\uc5d0 \ub530\ub77c \uc138\ubd84\ud654\ub429\ub2c8\ub2e4.
                                                          \nPD-1 \uc5b5\uc81c\uc81c \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \uc720\ud615 \uc138\uadf8\uba3c\ud2b8\ub294 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc57d 57 %\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4.
                                                          \nPD-1\uc774\ub77c\ub294 \uc5b5\uc81c\uc81c \uc218\uc6a9\uccb4\ub294 \ud504\ub85c\uadf8\ub7a8\ub41c \uc0ac\uba78 \uc2e0\ud638\ub97c \ud1b5\ud574 T\uc138\ud3ec \ub9e4\uac1c \ubc18\uc751\uc744 \uc870\uc808\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. PD-1\uc740 CD28 \uc790\uadf9 \uc2e0\ud638 \uacbd\ub85c\ub97c \ucc28\ub2e8\ud568\uc73c\ub85c\uc368 \uc138\ud3ec \uc99d\uc2dd\ubfd0\ub9cc \uc544\ub2c8\ub77c IL-2, IFN, TNF\ub97c \ud3ec\ud568\ud55c \uc0ac\uc774\ud1a0\uce74\uc778\uc758 \ubc29\ucd9c\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud65c\uc131\ud654\ub41c \ub2e8\ud575\uad6c, \uc790\uc5f0 \uc0b4\ud574 \uc138\ud3ec, \uc218\uc9c0\uc0c1 \uc138\ud3ec, T \uc138\ud3ec \ubc0f B \uc138\ud3ec\ub294 \uc885\uc591 \ubbf8\uc138 \ud658\uacbd(TME) \ub0b4\uc5d0\uc11c PD-1\uc744 \ubc1c\ud604\ud558\ub294 \uac83\uc73c\ub85c \ubc1d\ud600\uc9c4 \uba87 \uac00\uc9c0 \uba74\uc5ed \uc138\ud3ec \uc720\ud615\uc5d0 \ubd88\uacfc\ud569\ub2c8\ub2e4.
                                                          \nPD-1 \uacbd\ub85c\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uba74\uc5ed \uc694\ubc95\uc740 \uba54\ub974\ucf08\uc138\ud3ec\uc554, \ub450\uacbd\ubd80 \ud3b8\ud3c9\uc138\ud3ec\uc554(HNSCC), \ud751\uc0c9\uc885, \ube44\uc18c\uc138\ud3ec\ud3d0\uc554(NSCLC) \ub4f1 \ud2b9\uc815 \uc545\uc131 \uc885\uc591\uc758 \uce58\ub8cc \ubc29\uc2dd\uc744 \ubcc0\ud654\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub2c8\ubcfc\ub8e8\ub9d9, \ud3a8\ube0c\ub864\ub9ac\uc8fc\ub9d9, \uc138\ubbf8\ud50c\ub9ac\ub9d9 \ub4f1 \uc138 \uac00\uc9c0 \ub2e8\uc77c \ud074\ub860 \ud56d\uccb4\uac00 \ubbf8\uad6d FDA\uc5d0\uc11c PD-1 \uc5b5\uc81c\uc81c\ub85c \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.
                                                          \n2023\ub144 8\uc6d4 22\uc77c, \ube0c\ub9ac\uc2a4\ud1a8 \ub9c8\uc774\uc5b4\uc2a4 \uc2a4\ud034\ube0c\ub294 CheckMate -76K \uc784\uc0c1\uc2dc\ud5d8\uc758 \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c \uc720\ub7fd\uc5f0\ud569 \uc9d1\ud589\uc704\uc6d0\ud68c(EC)\ub85c\ubd80\ud130 \uc635\ub514\ubcf4(\ub2c8\ubcfc\ub8e8\ub9d9)\ub97c \ucd94\uac00\ub85c \uc644\uc804 \uc808\uc81c\uc220\uc744 \ubc1b\uc740 12\uc138 \uc774\uc0c1 \uccad\uc18c\ub144 \ubc0f \uc131\uc778 \ud751\uc0c9\uc885 IIB\uae30 \ub610\ub294 IIC\uae30 \ud658\uc790\uc758 \ubcf4\uc870 \uce58\ub8cc\ub97c \uc704\ud55c \ub2e8\ub3c5 \uce58\ub8cc\uc81c\ub85c \ud310\ub9e4\ud558\ub3c4\ub85d \uc2b9\uc778\ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc635\ub514\ubcf4\ub294 \ud604\uc7ac \uc808\uc81c\ub41c \ud751\uc0c9\uc885 IIB\uae30, IIC\uae30, III\uae30 \ubc0f IV\uae30 \ud658\uc790\uc5d0\uc11c \ubcf4\uc870 \uce58\ub8cc\uc81c\ub85c \uc2b9\uc778\ub41c \uc720\uc77c\ud55c PD-1 \uc5b5\uc81c\uc81c\uc785\ub2c8\ub2e4.
                                                          \n\uc9c0\ub9ac\uc801 \uc810\uc720\uc728
                                                          \n\ubd81\ubbf8 \uc9c0\uc5ed\uc740 2022\ub144 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc57d 37%\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4.
                                                          \n\uc758\ub8cc \ubd84\uc57c\uc5d0\uc11c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \ubd81\ubbf8 \uc9c0\uc5ed\uc758 \uc81c\uc870\uc5c5\uccb4\ub294 \uc6b4\uc601\uc744 \ub298\ub9b4 \uc218 \uc788\ub294 \uae30\ud68c\ub97c \uac16\uac8c \ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc758\ub8cc\uc5d0 \ub300\ud55c \uc9c0\ucd9c \uc99d\uac00, \uc5ec\ub7ec \uc9c8\ubcd1\uc5d0 \ub300\ud55c \uae30\uc220 \ubc0f \ub2e4\uc591\ud55c \uc720\ud615\uc758 \uc81c\ud488 \ubc1c\uc804, \ubc14\uc774\uc624 \uc81c\uc57d \ub610\ub294 \uc0dd\uba85 \uacf5\ud559 \uc0ac\uc5c5 \uc124\ub9bd\uc758 \uc99d\uac00\uc640 \ud568\uaed8 \uc774 \uc9c0\uc5ed\uc758 \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc131\uc7a5\uc5d0 \uae30\uc5ec\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                          \n\uc774 \ubd84\uc57c\uc758 \uc2dc\uc7a5\uc740 \uc5ec\ub7ec \uc81c\ud488 \ubc0f \uc801\uc751\uc99d\uc774 \ubbf8\uad6d FDA \ub610\ub294 EC\uc758 \uc2b9\uc778\uc744 \ubc1b\uc73c\uba74\uc11c \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc55e\uc11c \uc5b8\uae09\ud55c \uc694\uc18c\ub4e4\uc740 \ubd81\ubbf8\uac00 \uc138\uacc4\uc5d0\uc11c \ud5e4\uac8c\ubaa8\ub2c8\uc801 \uc704\uce58\ub97c \ucc28\uc9c0\ud558\uace0 \uc788\uc74c\uc744 \uc99d\uba85\ud569\ub2c8\ub2e4.
                                                          \n\ubd81\ubbf8\ub294 \uc804 \uc138\uacc4 \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc5d0\uc11c \uacc4\uc18d\ud574\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud558\uace0 \uc788\uc73c\uba70, \ubbf8\uad6d\uc774 \uc774\ub97c \uc8fc\ub3c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc778\ud504\ub77c \uac1c\ubc1c \ubc0f \ud22c\uc790\ub97c \ucd09\uc9c4\ud558\ub294 \uc815\ubd80 \uc774\ub2c8\uc154\ud2f0\ube0c\uc640 \uc99d\uac00\ud558\ub294 \ubc1c\uc804\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd98 \ubbf8\uad6d\uc758 \ub09c\uce58\uc131 \uc554\uc5d0 \ub300\ud55c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc5d0 \ub300\ud55c \uc218\uc694\ub294 \uc5ec\ub7ec \uc774\ub2c8\uc154\ud2f0\ube0c \ub610\ub294 \uc218\uc220 \uc808\ucc28\ub97c \uc801\uadf9\uc801\uc73c\ub85c \uc2e4\ud589\ud558\uc5ec \uc774\ub7ec\ud55c \uc57d\ubb3c \uc218\uc694\ub97c \uc790\uadf9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                          \n\ucf54\ub85c\ub09819 \uc601\ud5a5 \ubd84\uc11d
                                                          \n2019\ub144 \ub9d0 \ucf54\ub85c\ub09819 \ud32c\ub370\ubbf9\uc758 \ubc1c\ubc1c\ub85c \uc804 \uc138\uacc4 \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc744 \ube44\ub86f\ud55c \uc804 \uc138\uacc4 \uc0b0\uc5c5\uc5d0 \uc804\ub840 \uc5c6\ub294 \uc5b4\ub824\uc6c0\uc774 \ubc1c\uc0dd\ud588\uc2b5\ub2c8\ub2e4. \uac01\uad6d\uc774 \ubd09\uc1c4, \uacf5\uae09\ub9dd \uc911\ub2e8, \uacbd\uc81c \ud65c\ub3d9 \uac10\uc18c\ub85c \uc5b4\ub824\uc6c0\uc744 \uacaa\uc73c\uba74\uc11c \ub2e4\uc591\ud55c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c\uc758 \uc8fc\uc694 \uc18c\ube44\ucc98\uc778 \uc81c\uc57d \ubd80\ubb38\uc774 \ud070 \uc601\ud5a5\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. 2020\ub144 \ucd08\uc5d0 \uc2dc\uc791\ub41c \ud32c\ub370\ubbf9\uc73c\ub85c \uc778\ud55c \uad11\ubc94\uc704\ud55c \ubd09\uc1c4\uc640 \uc81c\ud55c\uc740 \uc804 \uc138\uacc4\uc758 \uc5ec\ub7ec \uc774\ub2c8\uc154\ud2f0\ube0c\uc5d0 \uc601\ud5a5\uc744 \ubbf8\ucce4\uc2b5\ub2c8\ub2e4.
                                                          \n\uc8fc\uc694 \uc758\ub8cc \ubc0f \uc0dd\uba85\uacf5\ud559 \uc0b0\uc5c5\uc774 \uba48\ucd94\uace0 \ucf54\ub85c\ub09819 \uad00\ub9ac\ub85c \uad00\uc2ec\uc744 \ub3cc\ub9ac\uba74\uc11c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uae09\uac10\ud588\uc2b5\ub2c8\ub2e4. \uc774\uc81c \uc5ec\ub7ec \uc5f0\uad6c\uac00 \uc2dc\uc791\ub418\uc5c8\uace0 \uae30\uc5c5\ub4e4\uc740 \ub2e4\uc2dc \uc81c\ud488 \ud6a8\uc728\uc131\uc5d0 \ub300\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc744 \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. \uc804\ubc18\uc801\uc73c\ub85c \ud32c\ub370\ubbf9\uc774 \uae00\ub85c\ubc8c \uccb4\ud06c\ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc740 \uc0c1\ub300\uc801\uc73c\ub85c \ud06c\uc9c0 \uc54a\uc744 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\uba70, PD-1 \uc5b5\uc81c\uc81c\uc640 \uac19\uc740 \ud601\uc2e0\uc801\uc778 \uc81c\ud488\uc5d0 \ub300\ud55c \uc9c0\uc18d\uc801\uc778 \uc218\uc694\uc640 \uc5f0\uad6c\ub85c \uc778\ud574 \uc2dc\uc7a5\uc740 \uafb8\uc900\ud788 \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
                                                          \n\uc8fc\uc694 \uac1c\ubc1c \ub3d9\ud5a5
                                                          \n2023\ub144 9\uc6d4 15\uc77c, \uba38\ud06c\uac00 \uac1c\ubc1c\ud55c \ud56d PD-1 \uce58\ub8cc\uc81c \ud0a4\ud2b8\ub8e8\ub2e4\ub294 \uc720\ub7fd\uc758\uc57d\ud488\uccad \uc57d\ubb3c\uc0ac\uc6a9\uc790\ubb38\uc704\uc6d0\ud68c(CHMP)\ub85c\ubd80\ud130 \uc885\uc591 \uc644\uc804 \uc81c\uac70 \ubc0f \ubc31\uae08 \uae30\ubc18 \ud654\ud559\uc694\ubc95 \ud6c4 \uc7ac\ubc1c \uac00\ub2a5\uc131\uc774 \ub192\uc740 \ube44\uc18c\uc138\ud3ec\ud3d0\uc554(NSCLC) \ud658\uc790\uc758 \ubcf4\uc870 \uc694\ubc95\uc73c\ub85c \uc2b9\uc778\uc744 \uad8c\uace0\ubc1b\uc558\uc2b5\ub2c8\ub2e4.
                                                          \n2023\ub144 3\uc6d4 9\uc77c, \uc808\uc81c \uac00\ub2a5\ud55c \ucd08\uae30 \ube44\uc18c\uc138\ud3ec\ud3d0\uc554(NSCLC) \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \uc218\uc220 \uc804 \uc2e0\ubcf4\uc870 \ud654\ud559\uc694\ubc95 \ubc0f \uc218\uc220 \ud6c4 \ubcf4\uc870 \ub2e8\ub3c5\uc694\ubc95\uc73c\ub85c \uc784\ud540\uc9c0(\uc131\ubd84\uba85: \ub354\ubc1c\ub8e8\ub9d9) \uce58\ub8cc\ub97c \uc2dc\ud589\ud55c \uacb0\uacfc, \uc2e0\ubcf4\uc870 \ud654\ud559\uc694\ubc95\ub9cc \uc2dc\ud589\ud55c \ud6c4 \uc218\uc220 \uce58\ub8cc\ub97c \ubc1b\uc740 \ud658\uc790 \ub300\ube44 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ubbf8\ud558\uace0 \uc2e4\uc9c8\uc801\uc778 \uc0dd\uc874\uae30\uac04 \uc5f0\uc7a5 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\uace0 AEGEAN 3\uc0c1 \uc704\uc57d \ub300\uc870 \uc2dc\ud5d8\uc758 \uc608\uc0c1 \uc911\uac04 \ud3c9\uac00 \uacb0\uacfc\uc5d0\uc11c \uace0\ubb34\uc801\uc73c\ub85c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.
                                                          \n\ub85c\uc288 \uadf8\ub8f9\uc758 \uc790\ud68c\uc0ac\uc778 \uc81c\ub128\ud14d\uc7402022\ub144 12\uc6d4 9\uc77c, \uc804\uc774\uc131 \ub610\ub294 \uc808\uc81c \ubd88\uac00\ub2a5\ud55c \ud3d0\ud3ec \uc5f0\ubd80 \uc721\uc885(ASPS)\uc774 \uc788\ub294 \uc131\uc778\uacfc 2\uc138 \uc774\uc0c1\uc758 \uc18c\uc544 \ud658\uc790 \uad00\ub9ac\ub97c \uc704\ud574 \ud14c\uc388\ud2b8\ub9ad(\uc131\ubd84\uba85: \uc544\ud14c\uc878\ub9ac\uc8fc\ub9d9)\uc5d0 \ub300\ud55c FDA \uc2b9\uc778\uc744 \ud68d\ub4dd\ud588\uc2b5\ub2c8\ub2e4. \uc80a\uc740 \ud658\uc790\uc77c\uc218\ub85d \uc9c4\ub2e8 \uc2dc \uc774\ubbf8 \uc9c4\ud589\ub418\uc5b4 \uc218\ub144\uc5d0 \uac78\uccd0 \uc11c\uc11c\ud788 \ud37c\uc9c0\uace0 \uc218\uc220 \ud6c4\uc5d0\ub3c4 \uc790\uc8fc \uc7ac\ubc1c\ud558\ub294 \ud76c\uadc0\ud558\uace0 \uad50\ubb18\ud55c \uc5f0\uc870\uc9c1 \uc721\uc885\uc778 ASPS\uc5d0 \uac78\ub9b4 \ud655\ub960\uc774 \ub192\uc2b5\ub2c8\ub2e4.<\/p>\n

                                                          \ubcf4\uace0\uc11c\ub97c \uad6c\ub9e4\ud558\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00\uc694?
                                                          \n\uba74\uc5ed \uad00\ubb38 \uc5b5\uc81c\uc81c \uc720\ud615, \uc9c8\ubcd1 \uc720\ud615 \ubc0f \uc9c0\uc5ed\uc5d0 \ub530\ub77c \uae00\ub85c\ubc8c \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5 \uc138\ubd84\ud654\ub97c \uc2dc\uac01\ud654\ud558\uace0 \uc8fc\uc694 \uc0c1\uc5c5 \uc790\uc0b0 \ubc0f \ud50c\ub808\uc774\uc5b4\ub97c \uc774\ud574\ud569\ub2c8\ub2e4.
                                                          \n\ub3d9\ud5a5\uacfc \uacf5\ub3d9 \uac1c\ubc1c\uc744 \ubd84\uc11d\ud558\uc5ec \uc0c1\uc5c5\uc801 \uae30\ud68c\ub97c \ud30c\uc545\ud569\ub2c8\ub2e4.
                                                          \n\ubaa8\ub4e0 \uc138\uadf8\uba3c\ud2b8\uc5d0 \ub300\ud55c \uccb4\ud06c \ud3ec\uc778\ud2b8 \uc5b5\uc81c\uc81c \ubd88\uc751\uc131 \uc554 \uc2dc\uc7a5 \uc218\uc900\uc758 \uc218\ub9ce\uc740 \ub370\uc774\ud130 \ud3ec\uc778\ud2b8\uac00 \ud3ec\ud568 \ub41c Excel \ub370\uc774\ud130 \uc2dc\ud2b8.
                                                          \nPDF \ubcf4\uace0\uc11c\ub294 \ucca0\uc800\ud55c \uc815\uc131\uc801 \uc778\ud130\ubdf0\uc640 \uc2ec\uce35 \uc5f0\uad6c\ub97c \uac70\uce5c \uc885\ud569\uc801\uc778 \ubd84\uc11d\uc73c\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.
                                                          \n\ubaa8\ub4e0 \uc8fc\uc694 \uc5c5\uccb4\uc758 \uc8fc\uc694 \uc81c\ud488\uc73c\ub85c \uad6c\uc131\ub41c \uc81c\ud488 \ub9e4\ud551\uc744 \uc5d1\uc140\ub85c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-16806","post","type-post","status-publish","format-standard","hentry","category-market-report"],"_links":{"self":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/16806"}],"collection":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/comments?post=16806"}],"version-history":[{"count":0,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/16806\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/media?parent=16806"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/categories?post=16806"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/tags?post=16806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}