{"id":19461,"date":"2025-02-06T17:21:49","date_gmt":"2025-02-06T17:21:49","guid":{"rendered":"https:\/\/www.mizuho.kr\/?p=5325"},"modified":"2026-09-13T16:39:10","modified_gmt":"2026-09-13T07:39:10","slug":"chronic-lower-back-pain-drugs-market-datam","status":"publish","type":"post","link":"https:\/\/www.globalresearch.co.kr\/insight\/chronic-lower-back-pain-drugs-market-datam\/","title":{"rendered":"\uae00\ub85c\ubc8c \ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5 : \uc57d\ubb3c \ub4f1\uae09\ubcc4 (\ube44\uc2a4\ud14c\ub85c\uc774\ub4dc \uc131 \ud56d\uc5fc\uc99d\uc81c (NSAID), \uc9c4\ud1b5\uc81c, \ud56d\uc6b0\uc6b8\uc81c, \uc624\ud53c\uc624\uc774\ub4dc, \uae30\ud0c0)"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5326\" src=\"https:\/\/www.mizuho.kr\/wp-content\/uploads\/2025\/02\/1-131.png\" alt=\"\" width=\"1350\" height=\"668\" \/><\/p>\n<p>&nbsp;<\/p>\n<ol>\n<li><b>\ubc29\ubc95\ub860 \ubc0f \ubc94\uc704<\/b>\n<ol>\n<li>\uc5f0\uad6c \ubc29\ubc95\ub860<\/li>\n<li>\ubcf4\uace0\uc11c\uc758 \uc5f0\uad6c \ubaa9\uc801 \ubc0f \ubc94\uc704<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc815\uc758 \ubc0f \uac1c\uc694<\/b><\/li>\n<li><b>\uc784\uc6d0 \uc694\uc57d<\/b>\n<ol>\n<li>\uc57d\ubb3c \uc885\ub958\ubcc4 \uc694\uc57d<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n<li>\uc9c0\uc5ed\ubcc4 \uc2a4\ub2c8\ud3ab<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc5ed\ud559<\/b>\n<ol>\n<li>\uc601\ud5a5 \uc694\uc778\n<ol>\n<li>\ub3d9\uc778\n<ol>\n<li>\uc758\uc57d\ud488 \uc784\uc0c1\uc2dc\ud5d8 \uc99d\uac00<\/li>\n<li>\uace8\uad00\uc808\uc5fc \uc720\ubcd1\ub960 \uc99d\uac00<\/li>\n<\/ol>\n<\/li>\n<li>\uc81c\uc57d\n<ol>\n<li>\uc57d\ubb3c\uc758 \uc548\uc804 \ubb38\uc81c<\/li>\n<\/ol>\n<\/li>\n<li>\uae30\ud68c<\/li>\n<li>\uc601\ud5a5 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc0b0\uc5c5 \ubd84\uc11d<\/b>\n<ol>\n<li>\ud3ec\ud130\uc758 \ub2e4\uc12f \uac00\uc9c0 \ud798 \ubd84\uc11d<\/li>\n<li>\uacf5\uae09\ub9dd \ubd84\uc11d<\/li>\n<li>\uac00\uaca9 \ubd84\uc11d<\/li>\n<li>\uaddc\uc81c \ubd84\uc11d<\/li>\n<li>\ud30c\uc774\ud504\ub77c\uc778 \ubd84\uc11d<\/li>\n<li>\ud2b9\ud5c8 \ubd84\uc11d<\/li>\n<li>\ub7ec\uc2dc\uc544-\uc6b0\ud06c\ub77c\uc774\ub098 \ubd84\uc7c1 \ubd84\uc11d<\/li>\n<li>DMI \uc758\uacac<\/li>\n<\/ol>\n<\/li>\n<li><b>\ucf54\ub85c\ub09819 \ubd84\uc11d<\/b>\n<ol>\n<li>\ucf54\ub85c\ub09819 \ubd84\uc11d\n<ol>\n<li>\ucf54\ub85c\ub098 \uc774\uc804 \uc2dc\ub098\ub9ac\uc624<\/li>\n<li>\ucf54\ub85c\ub09819 \uc911 \uc2dc\ub098\ub9ac\uc624<\/li>\n<li>\ucf54\ub85c\ub098 \uc774\ud6c4 \uc2dc\ub098\ub9ac\uc624<\/li>\n<\/ol>\n<\/li>\n<li>\ucf54\ub85c\ub09819\uc5d0 \ub530\ub978 \uac00\uaca9 \uc5ed\ud559<\/li>\n<li>\uc218\uc694-\uacf5\uae09 \uc2a4\ud399\ud2b8\ub7fc<\/li>\n<li>\ud32c\ub370\ubbf9 \uae30\uac04 \uc911 \uc2dc\uc7a5\uacfc \uad00\ub828\ub41c \uc815\ubd80 \uc774\ub2c8\uc154\ud2f0\ube0c<\/li>\n<li>\uc81c\uc870\uc5c5\uccb4\uc758 \uc804\ub7b5\uc801 \uc774\ub2c8\uc154\ud2f0\ube0c<\/li>\n<li>\uacb0\ub860<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc57d\ubb3c \uc885\ub958\ubcc4<\/b>\n<ol>\n<li>\uc18c\uac1c\n<ol>\n<li>\uc57d\ubb3c \ud074\ub798\uc2a4\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\uc758\uc57d\ud488 \ubd84\ub958\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n<li>\ube44\uc2a4\ud14c\ub85c\uc774\ub4dc\uc131 \ud56d\uc5fc\uc99d\uc81c(NSAID)*\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\uc774\ubd80\ud504\ub85c\ud39c(\uc560\ub4dc\ube4c, \ubaa8\ud2b8\ub9b0)<\/li>\n<li>\ub098\ud504\ub85d\uc13c(\uc54c\ub808\ube0c)<\/li>\n<li>\uc140\ub808\ucf55\uc2dc\ube0c(\uc384\ub808\ube0c\ub809\uc2a4)<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li>\uc9c4\ud1b5\uc81c\n<ol>\n<li>\uc544\uc138\ud2b8\uc544\ubbf8\ub178\ud39c(\ud0c0\uc774\ub808\ub180)<\/li>\n<li>\ud2b8\ub77c\ub9c8\ub3cc(\uc6b8\ud2b8\ub77c)<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li>\ud56d\uc6b0\uc6b8\uc81c\n<ol>\n<li>\uc544\ubbf8\ud2b8\ub9bd\ud2f8\ub9b0(\uc5d8\ub77c\ube4c)<\/li>\n<li>\ub458\ub85d\uc138\ud2f4(\uc2ec\ubc1c\ud0c0)<\/li>\n<li>\ubca4\ub77c\ud30d\uc2e0(\uc774\ud399\uc11c)<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li>\uc624\ud53c\uc624\uc774\ub4dc\n<ol>\n<li>\uc625\uc2dc\ucf54\ub3c8<\/li>\n<li>\ud558\uc774\ub4dc\ub85c\ucf54\ub3c8<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li><b>\ud22c\uc5ec \uacbd\ub85c\ubcc4<\/b>\n<ol>\n<li>\uc18c\uac1c\n<ol>\n<li>\ud22c\uc5ec \uacbd\ub85c\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218, \ud22c\uc5ec \uacbd\ub85c\ubcc4<\/li>\n<\/ol>\n<\/li>\n<li>\uacbd\uad6c*\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<\/ol>\n<\/li>\n<li>Topical<\/li>\n<li>\uadfc\uc721 \ub0b4(IM)<\/li>\n<li>\uae30\ud0c0<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc720\ud1b5 \ucc44\ub110\ubcc4<\/b>\n<ol>\n<li>\uc18c\uac1c\n<ol>\n<li>\uc720\ud1b5 \ucc44\ub110\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n<li>\ubcd1\uc6d0 \uc57d\uad6d*\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144\ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d (%)<\/li>\n<\/ol>\n<\/li>\n<li>\uc18c\ub9e4 \uc57d\uad6d<\/li>\n<li>\uc628\ub77c\uc778 \uc57d\uad6d<\/li>\n<\/ol>\n<\/li>\n<li><b>\uc9c0\uc5ed\ubcc4<\/b>\n<ol>\n<li>\uc18c\uac1c\n<ol>\n<li>\uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\uc9c0\uc5ed\ubcc4 \uc2dc\uc7a5 \ub9e4\ub825\ub3c4 \uc9c0\uc218<\/li>\n<\/ol>\n<\/li>\n<li>\ubd81\ubbf8\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559\uad00\uacc4<\/li>\n<li>\uc57d\ubb3c \ud074\ub798\uc2a4 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n<ol>\n<li>\ubbf8\uad6d<\/li>\n<li>Canada<\/li>\n<li>\uba55\uc2dc\ucf54<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li>\uc720\ub7fd\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n<li>\uc57d\ubb3c \ud074\ub798\uc2a4\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n<ol>\n<li>\ub3c5\uc77c<\/li>\n<li>\uc601\uad6d<\/li>\n<li>\ud504\ub791\uc2a4<\/li>\n<li>\uc774\ud0c8\ub9ac\uc544<\/li>\n<li>\uc2a4\ud398\uc778<\/li>\n<li>\uae30\ud0c0 \uc720\ub7fd<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li>\ub0a8\ubbf8\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n<li>\uc57d\ubb3c \uc885\ub958\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n<ol>\n<li>\ube0c\ub77c\uc9c8<\/li>\n<li>\uc544\ub974\ud5e8\ud2f0\ub098<\/li>\n<li>\uae30\ud0c0 \ub0a8\ubbf8<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li>\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n<li>\uc57d\ubb3c \ud074\ub798\uc2a4\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uad6d\uac00 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)\n<ol>\n<li>\uc911\uad6d<\/li>\n<li>\uc778\ub3c4<\/li>\n<li>\uc77c\ubcf8<\/li>\n<li>\ud638\uc8fc<\/li>\n<li>\uae30\ud0c0 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li>\uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74\n<ol>\n<li>\uc18c\uac1c<\/li>\n<li>\uc8fc\uc694 \uc9c0\uc5ed\ubcc4 \uc5ed\ud559 \uad00\uacc4<\/li>\n<li>\uc57d\ubb3c \ud074\ub798\uc2a4\ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5\ub960 \ubd84\uc11d(%)<\/li>\n<li>\ud22c\uc5ec \uacbd\ub85c \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<li>\uc720\ud1b5 \ucc44\ub110 \ubcc4 \uc2dc\uc7a5 \uaddc\ubaa8 \ubd84\uc11d \ubc0f \uc804\ub144 \ub300\ube44 \uc131\uc7a5 \ubd84\uc11d (%)<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li><b>\uacbd\uc7c1 \ud658\uacbd<\/b>\n<ol>\n<li>\uacbd\uc7c1 \uc2dc\ub098\ub9ac\uc624<\/li>\n<li>\uc2dc\uc7a5 \ud3ec\uc9c0\uc154\ub2dd\/\uc810\uc720\uc728 \ubd84\uc11d<\/li>\n<li>\uc778\uc218\ud569\ubcd1 \ubd84\uc11d<\/li>\n<\/ol>\n<\/li>\n<li><b>\uae30\uc5c5 \ud504\ub85c\ud544<\/b><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5327\" src=\"https:\/\/www.mizuho.kr\/wp-content\/uploads\/2025\/02\/2-93.png\" alt=\"\" width=\"1362\" height=\"394\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uae00\ub85c\ubc8c \ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5\uc740 2024-2031\ub144 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \ub192\uc740 CAGR\uc5d0 \ub3c4\ub2ec\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n\ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c\uc740 \uc9c0\uc18d\uc801\uc774\uace0 \uc7a5\uae30\uc801\uc778 \uc694\ud1b5\uc744 \uad00\ub9ac\ud558\ub294 \ub370 \uc0ac\uc6a9\ub418\ub294 \uc57d\ubb3c\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc720\ud615\uc758 \ud1b5\uc99d\uc740 \uc77c\ubc18\uc801\uc73c\ub85c 12\uc8fc \uc774\uc0c1 \uc9c0\uc18d\ub418\uba70 \uadfc\uace8\uaca9\uacc4 \ubb38\uc81c, \ud1f4\ud589\uc131 \uc9c8\ud658, \ubd80\uc0c1 \ub610\ub294 \ucc99\ucd94\uc758 \uad6c\uc870\uc801 \uc774\uc0c1 \ub4f1 \ub2e4\uc591\ud55c \uadfc\ubcf8\uc801\uc778 \uc6d0\uc778\uc73c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc57d\ubb3c\uc740 \ud1b5\uc99d\uc744 \uc644\ud654\ud558\uace0 \uc5fc\uc99d\uc744 \uc904\uc774\uba70 \uc694\ud1b5 \ud658\uc790\uc758 \uc0b6\uc758 \uc9c8\uc744 \uac1c\uc120\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud569\ub2c8\ub2e4.<br \/>\n\ub9cc\uc131 \uc694\ud1b5 \uce58\ub8cc\uc81c\ub294 \ube44\uc2a4\ud14c\ub85c\uc774\ub4dc\uc131 \ud56d\uc5fc\uc99d\uc81c, \uc9c4\ud1b5\uc81c, \ud56d\uc6b0\uc6b8\uc81c, \uc624\ud53c\uc624\uc774\ub4dc \ub4f1 \ub2e4\uc591\ud55c \uc885\ub958\uc758 \uc57d\ubb3c\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4. \ub610\ud55c \ub9cc\uc131 \uc694\ud1b5\uc758 \uc720\ubcd1\ub960 \uc99d\uac00\uc640 \uc57d\ubb3c \uc784\uc0c1 \uc2dc\ud5d8 \uc99d\uac00\ub294 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uc2dc\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uc694\uc778\uc785\ub2c8\ub2e4.<\/p>\n<p>\ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5 \uc5ed\ud559<br \/>\n\uc758\uc57d\ud488 \uc784\uc0c1\uc2dc\ud5d8 \uc99d\uac00\uac00 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uacac\uc778\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\nClinicalTrials.Gov\uc5d0 \ub530\ub974\uba74, \ub9cc\uc131 \ube44\ud2b9\uc774\uc801 \uc694\ud1b5 \ud658\uc790 \uce58\ub8cc\ub97c \uc704\ud574 Vertanical GmbH\uac00 \uc2e4\uc2dc\ud55c VER-01\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc740 2021\ub144 7\uc6d4 7\uc77c\uc5d0 \uc2dc\uc791\ub418\uc5b4 2023\ub144 10\uc6d4 16\uc77c\uae4c\uc9c0 1\ucc28 \uc644\ub8cc\ub420 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\uba70 \uc804\uccb4 \uc5f0\uad6c \uc644\ub8cc\uc77c\uc740 2024\ub144 5\uc6d4 27\uc77c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n\uc774 \ud0c0\uc784\ub77c\uc778\uc740 \ub9cc\uc131 \ube44\ud2b9\uc774\uc801 \uc694\ud1b5\uc744 \ud574\uacb0\ud558\uae30 \uc704\ud574 \uc124\uacc4\ub41c \uc7a0\uc7ac\uc801 \uc57d\ubb3c\uc778 VER-01\uc5d0 \ub300\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc758 \uac1c\uc694\ub97c \uc124\uba85\ud569\ub2c8\ub2e4. VER-01\uc774 \ub9cc\uc131 \uc694\ud1b5\uc744 \uc644\ud654\ud558\ub294 \ub370 \ud6a8\uacfc\uc801\uc774\uace0 \uc548\uc804\uc131 \ud504\ub85c\ud30c\uc77c\ub3c4 \uc591\ud638\ud55c \uac83\uc73c\ub85c \ud655\uc778\ub418\uba74 \uc774 \uc9c8\ud658\uc5d0 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub294 \uce58\ub8cc \uc635\uc158\uc758 \ubc94\uc704\uc5d0 \uc911\uc694\ud55c \ucd94\uac00\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc758\ub8cc\uc9c4\uacfc \ud658\uc790\ub4e4\uc758 \uc774 \uc57d\uc5d0 \ub300\ud55c \uc218\uc694 \uc99d\uac00\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n\uace8\uad00\uc808\uc5fc \uc720\ubcd1\ub960 \uc99d\uac00\uac00 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uacac\uc778\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n\uad00\uc808\uc5fc \ubc0f \ub958\uba38\ud2f0\uc998 \uc800\ub110\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uace8\uad00\uc808\uc5fc(OA)\uc758 \uc720\ubcd1\ub960\uc740 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uc8fc\uc694 \uacf5\uc911 \ubcf4\uac74 \ubb38\uc81c\uc785\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 2019\ub144 \uae00\ub85c\ubc8c \uc9c8\ubcd1 \ubd80\ub2f4 \uc5f0\uad6c \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 \uc5f0\ub839 \ud45c\uc900\ud654 OA \ube44\uc728\uc774 \uc9c0\uc18d\uc801\uc73c\ub85c \uc99d\uac00\ud558\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<br \/>\n\uac70\uc758 30\ub144 \ub3d9\uc548 \uace8\uad00\uc808\uc5fc(OA) \ud658\uc790 \uc218\ub294 \ub450 \ubc30 \uc774\uc0c1 \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. 1990\ub144 2\uc5b5 4,751\ub9cc \uac74\uc5d0\uc11c 2019\ub144 5\uc5b5 2,781\ub9cc \uac74\uc73c\ub85c \uc99d\uac00\ud588\uc73c\uba70, \ud2b9\ud788 \ubb34\ub98e\uacfc \uace0\uad00\uc808\uc5d0\uc11c \ub450\ub4dc\ub7ec\uc9c4 \uc99d\uac00 \ucd94\uc138\ub97c \ubcf4\uc774\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ud2b9\ud788 \ud070 \uad00\uc808\uc758 \uacbd\uc6b0 \uc2ec\uac01\ud55c \uc7a5\uc560\ub97c \ucd08\ub798\ud558\uace0 \uc2ec\uc9c0\uc5b4 \uad00\uc808 \uad50\uccb4\uac00 \ud544\uc694\ud560 \uc218 \uc788\ub294 \ud1f4\ud589\uc131\uad00\uc808\uc5fc\uc774 \uc5bc\ub9c8\ub098 \ud070 \ubd80\ub2f4\uc744 \uc8fc\ub294\uc9c0 \uc798 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<br \/>\n\ub530\ub77c\uc11c \uc758\ub8cc \uc11c\ube44\uc2a4 \uc81c\uacf5\uc790\ub294 \uc99d\uac00\ud558\ub294 OA \uc720\ubcd1\ub960\uc744 \ud574\uacb0\ud558\uae30 \uc704\ud574 \ubcf4\ub2e4 \ud3ec\uad04\uc801\uc778 \ud1b5\uc99d \uad00\ub9ac \uc804\ub7b5\uc744 \uc6b0\uc120\uc801\uc73c\ub85c \uc2dc\ud589\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub610\ud55c OA\ubfd0\ub9cc \uc544\ub2c8\ub77c \uadfc\uace8\uaca9\uacc4 \ubb38\uc81c\uc640 \uad00\ub828\ub41c \ub9cc\uc131 \uc694\ud1b5\uacfc \uac19\uc740 \uc9c8\ud658\uc5d0 \ub300\ud55c \ud6a8\uacfc\uc801\uc778 \ud1b5\uc99d \uc644\ud654 \uc635\uc158\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \ub9cc\uc131 \uc694\ud1b5 \uce58\ub8cc\uc81c \uc2dc\uc7a5\uc5d0\ub3c4 \uc7a0\uc7ac\uc801\uc73c\ub85c \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n\uc57d\ubb3c\uc758 \uc548\uc804\uc131 \ubb38\uc81c\uac00 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uc800\ud574\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub428<br \/>\n\ub9cc\uc131 \uc694\ud1b5\uc744 \uce58\ub8cc\ud558\ub294 \uc57d\ubb3c \uc2dc\uc7a5\uc740 \uc624\ud53c\uc624\uc774\ub4dc \uc704\uae30\ub85c \uc778\ud574 \ud070 \uc601\ud5a5\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc625\uc2dc\ucf54\ub3c8\uacfc \ud558\uc774\ub4dc\ub85c\ucf54\ub3c8\uacfc \uac19\uc740 \uc624\ud53c\uc624\uc774\ub4dc\ub294 \ud1b5\uc99d \uc644\ud654\uc5d0 \ud6a8\uacfc\uc801\uc774\uae30 \ub54c\ubb38\uc5d0 \uc774\uc804\uc5d0\ub294 \ub9ce\uc774 \ucc98\ubc29\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc911\ub3c5, \uacfc\ub2e4 \ubcf5\uc6a9 \ubc0f \uae30\ud0c0 \ubd80\uc791\uc6a9\uc758 \uc704\ud5d8\uc73c\ub85c \uc778\ud574 \uc774\ub7ec\ud55c \uc57d\ubb3c\uc740 \uc774\uc81c \ub354 \uc5c4\uaca9\ud55c \uaddc\uc81c\uc640 \ub354 \ub9ce\uc740 \uc870\uc0ac\ub97c \ubc1b\uac8c \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<br \/>\n\ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5 \uc138\ubd84 \ubd84\uc11d<br \/>\n\uae00\ub85c\ubc8c \ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5\uc740 \uc57d\ubb3c \uc885\ub958, \ud22c\uc5ec \uacbd\ub85c, \uc720\ud1b5 \ucc44\ub110 \ubc0f \uc9c0\uc5ed\uc5d0 \ub530\ub77c \uc138\ubd84\ud654\ub429\ub2c8\ub2e4.<br \/>\n\uc57d\ubb3c \ud074\ub798\uc2a4 \uc138\uadf8\uba3c\ud2b8\uc758 \ube44 \uc2a4\ud14c\ub85c\uc774\ub4dc \uc131 \ud56d\uc5fc\uc99d\uc81c (NSAID)\ub294 \ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc57d 37.6 %\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4.<br \/>\n\ube44\uc2a4\ud14c\ub85c\uc774\ub4dc\uc131 \ud56d\uc5fc\uc99d\uc81c(NSAID)\ub294 \ud1b5\uc99d\uacfc \uc5fc\uc99d\uc744 \uad00\ub9ac\ud558\uae30 \uc704\ud574 \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub418\ub294 \uc57d\ubb3c\uc758 \uc77c\uc885\uc785\ub2c8\ub2e4. \ub9cc\uc131 \uc694\ud1b5\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud574 \uac00\uc7a5 \uba3c\uc800 \uc120\ud0dd\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4.<br \/>\nNSAID\ub294 \uc2e0\uccb4\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \ud1b5\uc99d\uc744 \uc904\uc774\ub294 \ub370 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \ub9cc\uc131 \uc694\ud1b5\uc5d0\ub294 \uc5fc\uc99d\uc774 \ub3d9\ubc18\ub418\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc73c\uba70, \uc774\ub294 \ud1b5\uc99d\uc758 \ubd88\ud3b8\ud568\uacfc \uc2ec\uac01\uc131\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. NSAID\ub294 \uc0ac\uc774\ud074\ub85c\uc625\uc2dc\uac8c\ub098\uc81c(COX)\ub77c\ub294 \ud6a8\uc18c, \ud2b9\ud788 COX-1\uacfc COX-2\ub97c \uc5b5\uc81c\ud558\ub294 \ubc29\uc2dd\uc73c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4. \uc774 \ud6a8\uc18c\ub294 \ud1b5\uc99d, \ubc1c\uc5f4 \ubc0f \uc5fc\uc99d\uc744 \ucd09\uc9c4\ud558\ub294 \ud654\ud559\uc801 \uba54\uc2e0\uc800\uc778 \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518\uc758 \uc0dd\uc131\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. NSAID\ub294 COX \ud6a8\uc18c\ub97c \ucc28\ub2e8\ud568\uc73c\ub85c\uc368 \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518\uc758 \uc0dd\uc131\uc744 \uac10\uc18c\uc2dc\ucf1c \ud1b5\uc99d\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<br \/>\nNSAID\ub294 \ud1b5\uc99d \uc644\ud654\uc5d0 \ub3c4\uc6c0\uc774 \ub420 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ud574\ub2f9 \ubd80\uc704\uc758 \uc5fc\uc99d\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub9cc\uc131 \uc694\ud1b5\uc740 \uadfc\uc721 \uae34\uc7a5, \ubd80\uc0c1 \ub610\ub294 \uace8\uad00\uc808\uc5fc\uacfc \uac19\uc740 \ud1f4\ud589\uc131 \uc9c8\ud658\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \uc694\uc778\uc73c\ub85c \uc778\ud574 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc73c\uba70, \uc774 \ubaa8\ub4e0 \uc694\uc778\uc774 \uc5fc\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. NSAID\ub294 \uc5fc\uc99d \ubc18\uc751\uc744 \uc644\ud654\ud558\uc5ec \ud1b5\uc99d\uc744 \uc904\uc774\uace0 \uc774\ub3d9\uc131\uc744 \uac1c\uc120\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n\uc608\ub97c \ub4e4\uc5b4, \uc774\ubd80\ud504\ub85c\ud39c(\uc560\ub4dc\ube4c, \ubaa8\ud2b8\ub9b0), \ub098\ud504\ub85d\uc13c(\uc54c\ub808\ube0c), \uc140\ub808\ucf55\uc2dc\ube0c(\uc140\ub808\ube0c\ub809\uc2a4) \ub4f1\uc774 \ub9cc\uc131 \uc694\ud1b5\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uc77c\ubc18\uc758\uc57d\ud488\uc785\ub2c8\ub2e4. \ub610\ud55c \ud1b5\uc99d \ubc0f \uc5fc\uc99d \uad00\ub9ac\uc5d0 \ub300\ud55c \uc785\uc99d \ub41c \ud6a8\uacfc\ub85c \uc778\ud574 \uc26c\uc6b4 \uc811\uadfc\uc131, \uacbd\uc81c\uc131, \ud658\uc790 \uc120\ud638\ub3c4 \ubc0f \uc0c1\ud0dc\uc758 \ub9cc\uc131\uc801 \ud2b9\uc131\uc744 \ud574\uacb0\ud558\ub294 \ud45c\uc900 \uce58\ub8cc \uc635\uc158\uc73c\ub85c\uc11c\uc758 \uc5ed\ud560\uc774 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uc2dc\uc7a5\uc744 \uc8fc\ub3c4 \ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uc694\uc18c\uc785\ub2c8\ub2e4.<br \/>\n\ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c \uc2dc\uc7a5 \uc9c0\ub9ac\uc801 \uc810\uc720\uc728<br \/>\n\ubd81\ubbf8\ub294 \ub9cc\uc131 \uc694\ud1b5\uc758 \uc720\ubcd1\ub960 \uc99d\uac00\uc640 \uc784\uc0c1 \uc2dc\ud5d8 \uc99d\uac00\ub85c \uc778\ud574 2022 \ub144 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 \uc57d 40.3 %\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4.<br \/>\n\ubd81\ubbf8 \uc9c0\uc5ed\uc740 \ub9cc\uc131 \uc694\ud1b5\uc758 \uc720\ubcd1\ub960 \uc99d\uac00\uc640 \uc784\uc0c1 \uc2dc\ud5d8 \uc99d\uac00\ub85c \uc778\ud574 \uc608\uce21 \uae30\uac04 \ub3d9\uc548 \uac00\uc7a5 \ud070 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \ucc28\uc9c0\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ud074\ub9ac\ube14\ub79c\ub4dc \ud074\ub9ac\ub2c9\uc5d0 \ub530\ub974\uba74 \uc694\ud1b5\uc740 \uc0b6\uc758 \uc5b4\ub290 \uc2dc\uc810\uc5d0\uc11c 5\uba85 \uc911 4\uba85\uc5d0\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \ud754\ud55c \ubb38\uc81c\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ucde8\uc57d\uc131\uc740 \uc8fc\ub85c \ucc99\ucd94 \ubf08 \uc0ac\uc774\uc758 \ucfe0\uc158\uacfc \uac19\uc740 \ub514\uc2a4\ud06c\uac00 \uc9c0\uc18d\uc801\uc73c\ub85c \ud1f4\ud589\ud558\uae30 \ub54c\ubb38\uc774\uba70, 30\uc138 \uc774\ud6c4\uc5d0 \ub354 \ub9ce\uc774 \ubc1c\uc0dd\ud569\ub2c8\ub2e4.<br \/>\n\uc774 \uc678\uc5d0\ub3c4 \uacfc\uccb4\uc911\uacfc \uac19\uc740 \uc77c\ubd80 \uc694\uc778\uc774 \uc694\ud1b5 \ubc1c\ubcd1 \uc704\ud5d8\uc744 \ub192\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacfc\uccb4\uc911\uc740 \uad00\uc808\uacfc \ucc99\ucd94 \ub514\uc2a4\ud06c\uc5d0 \ucd94\uac00\uc801\uc778 \uc555\ub825\uc744 \uac00\ud558\uc5ec \ud1b5\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ud5c8\ub9ac \ub514\uc2a4\ud06c \ubc0f \ucc99\ucd94 \ud611\ucc29\uc99d\uacfc \uac19\uc740 \uc758\ud559\uc801 \uc9c8\ud658\uc73c\ub85c \uc778\ud574 \ud761\uc5f0, \uacfc\ub3c4\ud55c \uc74c\uc8fc \ubc0f \uc549\uc544\uc11c \uc0dd\ud65c\ud558\ub294 \uc0dd\ud65c \uc2b5\uad00\ub3c4 \uc694\ud1b5\uc758 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n\ub610\ud55c \uc6b0\uc6b8\uc99d\uacfc \ubd88\uc548\uc99d\uc744 \uc553\uace0 \uc788\ub294 \uc0ac\ub78c\uc77c\uc218\ub85d \uc694\ud1b5\uc774 \ubc1c\uc0dd\ud560 \uac00\ub2a5\uc131\uc774 \ub192\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ubd81\ubbf8 \ucc99\ucd94 \ud559\ud68c\ub294 \uacfc\uac70\uc5d0 \uae09\uc131 \uc694\ud1b5\uc744 \uacbd\ud5d8\ud55c \uc801\uc774 \uc788\ub294 \uc0ac\ub78c\uc740 \ub9cc\uc131 \uc99d\uc0c1\uc774 \ubc1c\uc0dd\ud560 \uc704\ud5d8\uc774 \ub354 \ub192\ub2e4\uace0 \ub9d0\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \ub9cc\uc131 \uc694\ud1b5 \uc57d\ubb3c\uc758 \uc218\uc694\uc640 \ucc44\ud0dd\uc774 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\ucf54\ub85c\ub09819 \uc601\ud5a5 \ubd84\uc11d<br \/>\n\ucf54\ub85c\ub09819 \ud32c\ub370\ubbf9\uc740 \ubd09\uc1c4\uc640 \uc0ac\ud68c\uc801 \uac70\ub9ac\ub450\uae30 \uc870\uce58\ub85c \uc778\ud574 \uc0ac\ub78c\ub4e4\uc758 \uc77c\uc0c1\uc5d0 \ud070 \ubcc0\ud654\ub97c \uac00\uc838\uc654\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc, \uc77c\ubd80 \uc0ac\ub78c\ub4e4\uc740 \ub354 \ub9ce\uc774 \uc549\uc544\uc11c \uc0dd\ud65c\ud558\uac8c \ub418\uc5b4 \ub9cc\uc131 \uc694\ud1b5\uc774 \uc545\ud654\ub418\uc5c8\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n\uc758\ub8cc \uc2dc\uc2a4\ud15c\uc774 \ucf54\ub85c\ub09819 \ud658\uc790 \uce58\ub8cc \uc218\uc694\uc5d0 \uc555\ub3c4\ub2f9\ud558\uba74\uc11c \ub9cc\uc131 \ud1b5\uc99d \uad00\ub9ac\uc640 \uac19\uc740 \uae34\uae09\ud558\uc9c0 \uc54a\uc740 \uc758\ub8cc \uc808\ucc28 \ubc0f \uc608\uc57d\uc774 \uc5f0\uae30\ub418\uac70\ub098 \ucde8\uc18c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uce58\ub8cc \uc9c0\uc5f0\uc740 \uc77c\ubd80 \ud658\uc790\ub4e4\uc774 \ucc98\ubc29\ub41c \uc57d\uc744 \ubcf5\uc6a9\ud558\ub294 \ub370 \uc601\ud5a5\uc744 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