{"id":42000,"date":"2026-02-13T21:17:32","date_gmt":"2026-02-13T21:17:32","guid":{"rendered":"https:\/\/www.globalresearch.co.kr\/insight\/friedreichs-ataxia-market-mordor\/"},"modified":"2026-10-02T05:31:56","modified_gmt":"2026-10-01T20:31:56","slug":"friedreichs-ataxia-market-mordor","status":"publish","type":"post","link":"https:\/\/www.globalresearch.co.kr\/insight\/friedreichs-ataxia-market-mordor\/","title":{"rendered":"\uc138\uacc4\uc758 \ud504\ub9ac\ub4dc\ub9ac\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5 \uaddc\ubaa8 \ubc0f \uc810\uc720\uc728 \ubd84\uc11d \u2013 \uc131\uc7a5 \ub3d9\ud5a5 \ubc0f \uc804\ub9dd (2025-2030\ub144)"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/www.globalresearch.co.kr\/insight\/wp-content\/uploads\/2026\/02\/friedreichs-ataxia-market-1762253310553-major-players.webp\" alt=\"Chart\" class=\"aligncenter size-full\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.globalresearch.co.kr\/insight\/wp-content\/uploads\/2026\/02\/friedreichs-ataxia-market-size-image-1765349283004.webp\" alt=\"Chart\" class=\"aligncenter size-full\" \/><\/p>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-0\">\n    1. \uc11c\ub860<\/p>\n<ul>\n<li class=\"toc-level-2\">\n          1.1 \uc5f0\uad6c \uac00\uc815 \ubc0f \uc2dc\uc7a5 \uc815\uc758<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          1.2 \uc5f0\uad6c \ubc94\uc704<\/p>\n<\/li>\n<\/ul>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-1\">\n    2. \uc5f0\uad6c \ubc29\ubc95\ub860<\/p>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-2\">\n    3. \uc694\uc57d<\/p>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-3\">\n    4. \uc2dc\uc7a5 \ud658\uacbd<\/p>\n<ul>\n<li class=\"toc-level-2\">\n          4.1 \uc2dc\uc7a5 \uac1c\uc694<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          4.2 \uc2dc\uc7a5 \ub3d9\uc778<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          4.2.1 \ucd5c\ucd08\uc758 \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\uc81c(\uc624\ub9c8\ubca8\ub85d\uc194\ub860) \uaddc\uc81c \uc2b9\uc778<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.2.2 \uc720\uc804\uc790 \uce58\ub8cc R&amp;D \ud22c\uc790 \uc99d\uac00<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.2.3 \ud658\uc790 \ub4f1\ub85d \ud655\ub300 \ubc0f \uc870\uae30 \uc9c4\ub2e8<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.2.4 \uc2e0\uc0dd\uc544 \uc120\ubcc4 \uac80\uc0ac \ud328\ub110 \ud655\uc7a5<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.2.5 AI \uae30\ubc18 \uc57d\ubb3c \uc7ac\ucc3d\ucd9c \ub178\ub825<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.2.6 \ucd08\ud76c\uadc0 \uc758\uc57d\ud488 \uc81c\uc870\uc5d0 \ub300\ud55c \ud76c\uadc0\uc758\uc57d\ud488 \uc138\uae08 \uc778\uc13c\ud2f0\ube0c<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          4.3 \uc2dc\uc7a5 \uc81c\uc57d<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          4.3.1 ROI\ub97c \uc81c\ud55c\ud558\ub294 \uc801\uc740 \ud658\uc790 \ud480<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.3.2 \ub192\uc740 \uce58\ub8cc \ube44\uc6a9 \ubc0f \uc0c1\ud658 \uc7a5\ubcbd<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.3.3 \uc720\uc804\uc790 \ubca1\ud130\uc5d0 \ub300\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub3c5\uc131 \uc6b0\ub824<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.3.4 \uc81c\ud55c\ub41c \uae00\ub85c\ubc8c \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130 \uc0dd\uc0b0 \ub2a5\ub825<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          4.4 \uacf5\uae09\ub9dd \ubd84\uc11d<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          4.5 \uaddc\uc81c \ud658\uacbd<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          4.6 \uae30\uc220 \uc804\ub9dd<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          4.7 \ud3ec\ud130\uc758 5\uac00\uc9c0 \uacbd\uc7c1 \uc694\uc778<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          4.7.1 \uc2e0\uaddc \uc9c4\uc785\uc790\uc758 \uc704\ud611<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.7.2 \uacf5\uae09\uc5c5\uccb4\uc758 \ud611\uc0c1\ub825<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.7.3 \uad6c\ub9e4\uc790\uc758 \ud611\uc0c1\ub825<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.7.4 \ub300\uccb4\uc7ac\uc758 \uc704\ud611<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          4.7.5 \uacbd\uc7c1 \uac15\ub3c4<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-4\">\n    5. \uc2dc\uc7a5 \uaddc\ubaa8 \ubc0f \uc131\uc7a5 \uc608\uce21 (\uac00\uce58-USD)<\/p>\n<ul>\n<li class=\"toc-level-2\">\n          5.1 \uce58\ub8cc \uc720\ud615\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.1.1 \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\ubc95<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.1.2 \uc720\uc804\uc790 \uce58\ub8cc\ubc95<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.1.3 \ub2e8\ubc31\uc9c8 \ub300\uccb4 \uce58\ub8cc\ubc95<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.1.4 RNA \uae30\ubc18 \uce58\ub8cc\ubc95<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.1.5 \uc99d\uc0c1 \uc644\ud654 \uce58\ub8cc\ubc95<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          5.2 \uc57d\ubb3c \ubd84\ub958\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.2.1 \ud56d\uc0b0\ud654\uc81c\/Nrf2 \ud65c\uc131\uc81c<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.2.2 PPAR \uc791\uc6a9\uc81c<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.2.3 \ud504\ub77c\ud0c1\uc2e0 \uc720\uc804\uc790 \ubca1\ud130 (AAV, \ub80c\ud2f0\ubc14\uc774\ub7ec\uc2a4)<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.2.4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc548\uc815\uc81c<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.2.5 \uae30\ud0c0<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          5.3 \ud22c\uc5ec \uacbd\ub85c\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.3.1 \uacbd\uad6c<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.3.2 \uc815\ub9e5 \uc8fc\uc0ac<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.3.3 \uc218\ub9c9\uac15\ub0b4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.3.4 \ud53c\ud558<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          5.4 \uc5f0\ub839 \uadf8\ub8f9\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.4.1 \uc18c\uc544 (<18\uc138)\n          \n        <\/li>\n<li class=\"toc-level-3\">\n          5.4.2 \uc131\uc778 (18\u201340\uc138)<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.4.3 \ud6c4\uae30 \ubc1c\ubcd1 (>40\uc138)<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          5.5 \uc720\ud1b5 \ucc44\ub110\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.5.1 \ubcd1\uc6d0 \uc57d\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.5.2 \uc804\ubb38 \uc57d\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.5.3 \uc628\ub77c\uc778 \uc57d\uad6d<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li class=\"toc-level-2\">\n          5.6 \uc9c0\uc5ed\ubcc4<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          5.6.1 \ubd81\ubbf8<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.1.1 \ubbf8\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.1.2 \uce90\ub098\ub2e4<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.1.3 \uba55\uc2dc\ucf54<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.6.2 \uc720\ub7fd<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.1 \ub3c5\uc77c<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.2 \uc601\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.3 \ud504\ub791\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.4 \uc774\ud0c8\ub9ac\uc544<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.5 \uc2a4\ud398\uc778<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.2.6 \uc720\ub7fd \uae30\ud0c0 \uc9c0\uc5ed<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.6.3 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.1 \uc911\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.2 \uc77c\ubcf8<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.3 \uc778\ub3c4<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.4 \ud638\uc8fc<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.5 \ub300\ud55c\ubbfc\uad6d<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.3.6 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uae30\ud0c0 \uc9c0\uc5ed<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.6.4 \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.4.1 GCC<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.4.2 \ub0a8\uc544\ud504\ub9ac\uce74<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.4.3 \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74 \uae30\ud0c0 \uc9c0\uc5ed<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          5.6.5 \ub0a8\ubbf8<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.5.1 \ube0c\ub77c\uc9c8<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.5.2 \uc544\ub974\ud5e8\ud2f0\ub098<\/p>\n<\/li>\n<li class=\"toc-level-4\">\n          5.6.5.3 \ub0a8\ubbf8 \uae30\ud0c0 \uc9c0\uc5ed<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-5\">\n    6. \uacbd\uc7c1 \ud658\uacbd<\/p>\n<ul>\n<li class=\"toc-level-2\">\n          6.1 \uc2dc\uc7a5 \uc9d1\uc911\ub3c4<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          6.2 \uc2dc\uc7a5 \uc810\uc720\uc728 \ubd84\uc11d<\/p>\n<\/li>\n<li class=\"toc-level-2\">\n          6.3 \ud68c\uc0ac \ud504\ub85c\ud544 (\uae00\ub85c\ubc8c \uc218\uc900 \uac1c\uc694, \uc2dc\uc7a5 \uc218\uc900 \uac1c\uc694, \ud575\uc2ec \ubd80\ubb38, \uc0ac\uc6a9 \uac00\ub2a5\ud55c \uc7ac\ubb34 \uc815\ubcf4, \uc804\ub7b5 \uc815\ubcf4, \uc8fc\uc694 \uae30\uc5c5\uc758 \uc2dc\uc7a5 \uc21c\uc704\/\uc810\uc720\uc728, \uc81c\ud488 \ubc0f \uc11c\ube44\uc2a4, \ucd5c\uadfc \uac1c\ubc1c \ud3ec\ud568)<\/p>\n<ul>\n<li class=\"toc-level-3\">\n          6.3.1 \uc544\uae30\uc624\uc2a4 \uc81c\uc57d<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.2 \ubc14\uc774\uc624\uc820<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.3 \ubc14\uc774\uc624\ud53c\ud2f0\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.4 \ud06c\ub9ac\uc2a4\ud37c \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.5 \uc5d0\ub514\ud0c0\uc2a4 \uba54\ub514\uc2a8<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.6 \ud5ec\ub9ad\uc2a4\ubbf8\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.7 \uc778\ud2b8\ub77c\ubc14\uc774\uc624<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.8 \ub809\uc138\uc624 \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.9 \ubbf8\ub178\ub9ad\uc2a4 \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.10 \ub178\ubc14\ud2f0\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.11 \ud504\ub85c\ud050\uc54c \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.12 PTC \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.13 \ub808\ud2b8\ub85c\ud1a0\ud504<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.14 \uc0b0\ud14c\ub77c \uc81c\uc57d<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.15 \uc2a4\ud30c\ud06c \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.16 \uc2a4\ud154\uc2a4 \ubc14\uc774\uc624\ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.17 \ub2e4\ucf00\ub2e4 \uc81c\uc57d<\/p>\n<\/li>\n<li class=\"toc-level-3\">\n          6.3.18 \ubcf4\uc774\uc800 \ud14c\ub77c\ud4e8\ud2f1\uc2a4<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p class=\"toc-level-1 toc-content-heading\" id=\"toc-content-heading-6\">\n    7. \uc2dc\uc7a5 \uae30\ud68c \ubc0f \ubbf8\ub798 \uc804\ub9dd<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5 \uaddc\ubaa8 \ubc0f \uc810\uc720\uc728 \ubd84\uc11d &#8211; \uc131\uc7a5 \ub3d9\ud5a5 \ubc0f \uc608\uce21 (2025-2030)<\/p>\n<p>\uc2dc\uc7a5 \uac1c\uc694<\/p>\n<p>\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d(Friedreich&#8217;s Ataxia, FA) \uc2dc\uc7a5\uc740 2025\ub144 11\uc5b5 2\ucc9c\ub9cc \ub2ec\ub7ec \uaddc\ubaa8\uc5d0\uc11c 2030\ub144\uae4c\uc9c0 20\uc5b5 7\ucc9c\ub9cc \ub2ec\ub7ec\uc5d0 \ub3c4\ub2ec\ud558\uba70 \uc5f0\ud3c9\uade0 13.04%\uc758 \uacac\uace0\ud55c \uc131\uc7a5\ub960\uc744 \uae30\ub85d\ud560 \uac83\uc73c\ub85c \uc804\ub9dd\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc131\uc7a5\uc740 \uc624\ub9c8\ubca8\ub85d\uc194\ub860(omaveloxolone)\uc758 \ub3d9\uae09 \ucd5c\ucd08 \uc2b9\uc778, \uc720\uc804\uc790 \uce58\ub8cc\uc81c \ud30c\uc774\ud504\ub77c\uc778\uc758 \uae09\uc99d, \uadf8\ub9ac\uace0 \uc870\uae30 \ud658\uc790 \uc2dd\ubcc4\uc744 \uc704\ud55c \uc2e0\uc0dd\uc544 \uc120\ubcc4 \uac80\uc0ac\uc758 \ud655\ub300\uc5d0 \ud798\uc785\uc740 \ubc14\uac00 \ud07d\ub2c8\ub2e4. \uc81c\uc870\uc0ac\ub4e4\uc774 \uc544\ub370\ub178 \uad00\ub828 \ubc14\uc774\ub7ec\uc2a4(AAV) \uc0dd\uc0b0 \ub2a5\ub825\uc744 \ud655\uc7a5\ud558\uae30 \uc704\ud574 \uacbd\uc7c1\ud558\uba74\uc11c \uc790\ubcf8 \uc720\uc785\uc774 \uac00\uc18d\ud654\ub418\uace0 \uc788\uc73c\uba70, \uc804\ubb38 \uc57d\uad6d \ub124\ud2b8\uc6cc\ud06c\ub294 \ucd08\ud76c\uadc0 \uc9c8\ud658 \uce58\ub8cc\uc81c\uc758 \ubb3c\ub958\ub97c \uac1c\uc120\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud22c\uc790\uc790\ub4e4\uc740 \uc9c0\uc18d\uc801\uc778 \uac00\uaca9 \uacb0\uc815\ub825\uc744 \uae30\ub300\ud558\uc9c0\ub9cc, \uc7a5\uae30\uc801\uc778 \uc131\uc7a5\uc740 \uc5ec\uc804\ud788 \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130 \ubcd1\ubaa9 \ud604\uc0c1 \ud574\uacb0\uacfc \uc9c0\ubd88\uc790\uc5d0\uac8c \uc218\uc6a9 \uac00\ub2a5\ud55c \ube44\uc6a9 \ud6a8\uc728\uc131 \ub370\uc774\ud130 \ud655\ubcf4\uc5d0 \ub2ec\ub824 \uc788\uc2b5\ub2c8\ub2e4. \ubca1\ud130 \uc0dd\uc0b0 \ubc0f \uc784\uc0c1 \uac1c\ubc1c\uc758 \uae30\uc220\uc801 \uc7a5\ubcbd\uc73c\ub85c \uc778\ud574 \uc2e0\uaddc \uc9c4\uc785\uc774 \uc81c\ud55c\uc801\uc774\ubbc0\ub85c \uacbd\uc7c1 \uac15\ub3c4\ub294 \uc911\uac04 \uc218\uc900\uc744 \uc720\uc9c0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\ud575\uc2ec \ubcf4\uace0\uc11c \uc694\uc57d<\/p>\n<p>*   \uce58\ub8cc \uc720\ud615\ubcc4: 2024\ub144 \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\uc81c(Disease-Modifying Drugs)\uac00 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 90.43%\ub97c \ucc28\uc9c0\ud588\uc73c\uba70, \uc720\uc804\uc790 \uce58\ub8cc\uc81c\ub294 2030\ub144\uae4c\uc9c0 \uc5f0\ud3c9\uade0 11.23%\ub85c \uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n*   \uc57d\ubb3c \ubd84\ub958\ubcc4: 2024\ub144 \ud56d\uc0b0\ud654\uc81c\/Nrf2 \ud65c\uc131\uc81c(Antioxidant\/Nrf2 Activators)\uac00 \uc2dc\uc7a5 \uaddc\ubaa8\uc758 88.56%\ub97c \uc810\uc720\ud588\uc73c\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc548\uc815\uc81c(Mitochondrial Stabilizers)\ub294 2030\ub144\uae4c\uc9c0 \uc5f0\ud3c9\uade0 10.52%\ub85c \ud655\uc7a5\ub420 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4.<br \/>\n*   \ud22c\uc5ec \uacbd\ub85c\ubcc4: 2024\ub144 \uacbd\uad6c\uc6a9 \uc81c\ud488\uc774 89.37%\uc758 \uc810\uc720\uc728\uc744 \uae30\ub85d\ud588\uc73c\uba70, \ucc28\uc138\ub300 \ubca1\ud130\uac00 \ud6c4\uae30 \uc784\uc0c1 \uc2dc\ud5d8 \ub2e8\uacc4\ub85c \uc9c4\uc785\ud568\uc5d0 \ub530\ub77c \uc218\ub9c9\uac15\ub0b4 \ud22c\uc5ec(Intrathecal Delivery)\ub294 \uc5f0\ud3c9\uade0 9.01%\ub85c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc5f0\ub839 \uadf8\ub8f9\ubcc4: 2024\ub144 \uc131\uc778(18-40\uc138)\uc774 \ub9e4\ucd9c\uc758 61.22%\ub97c \ucc28\uc9c0\ud588\uc73c\uba70, \ubc14\ud2f0\ud034\ub17c(vatiquinone)\uc758 \uc6b0\uc120 \uc2ec\uc0ac \uc2b9\uc778\uc5d0 \ud798\uc785\uc5b4 \uc18c\uc544 \uc0ac\uc6a9\uc774 \uc5f0\ud3c9\uade0 9.64%\ub85c \uac00\uc7a5 \ube60\ub974\uac8c \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc720\ud1b5 \ucc44\ub110\ubcc4: 2024\ub144 \uc804\ubb38 \uc57d\uad6d(Specialty Pharmacies)\uc774 68.62%\uc758 \uc810\uc720\uc728\uc744 \uae30\ub85d\ud588\uc73c\uba70, \uc720\uc804\uc790 \uce58\ub8cc\uc81c \uc8fc\uc785\uc774 3\ucc28 \uc758\ub8cc\uae30\uad00\uc73c\ub85c \uc804\ud658\ub428\uc5d0 \ub530\ub77c \ubcd1\uc6d0 \uc57d\uad6d(Hospital Pharmacies)\uc740 \uc5f0\ud3c9\uade0 11.89%\ub85c \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc9c0\uc5ed\ubcc4: 2024\ub144 \ubd81\ubbf8\uac00 \ub9e4\ucd9c\uc758 52.34%\ub97c \ucc28\uc9c0\ud588\uc73c\uba70, \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc740 \ud76c\uadc0 \uc9c8\ud658 \ub4f1\ub85d \ud655\ub300\uc5d0 \ud798\uc785\uc5b4 2030\ub144\uae4c\uc9c0 \uc5f0\ud3c9\uade0 9.47%\uc758 \uc131\uc7a5\ub960\uc744 \uae30\ub85d\ud560 \uac83\uc73c\ub85c \uc804\ub9dd\ub429\ub2c8\ub2e4.<\/p>\n<p>\uae00\ub85c\ubc8c \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5 \ub3d9\ud5a5 \ubc0f \ud1b5\ucc30<\/p>\n<p>\uc2dc\uc7a5 \uc131\uc7a5 \ub3d9\ub825 (Drivers):<\/p>\n<p>*   \ucd5c\ucd08 \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\uc81c \uc2b9\uc778 (\uc624\ub9c8\ubca8\ub85d\uc194\ub860): 2023\ub144 \uc624\ub9c8\ubca8\ub85d\uc194\ub860(\uc81c\ud488\uba85 SKYCLARYS)\uc758 \uc2b9\uc778\uc740 \uc99d\uc0c1 \uc644\ud654\uc5d0\ub9cc \ucd08\uc810\uc744 \ub9de\ucd94\ub358 \uae30\uc874 \ud328\ub7ec\ub2e4\uc784\uc744 \uc804\ud658\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \uc774 \uc57d\ubb3c\uc740 \uc218\uc815\ub41c \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \ud3c9\uac00 \ucc99\ub3c4(mFARS)\uc5d0\uc11c \uce21\uc815 \uac00\ub2a5\ud55c \uac1c\uc120\uc744 \ubcf4\uc600\uc73c\uba70, 2024\ub144 \uc720\ub7fd \uc2b9\uc778\uc73c\ub85c \uc811\uadfc\uc131\uc774 \ud655\ub300\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc7a5\uae30 \ub370\uc774\ud130\ub294 \uae30\ub2a5 \uc800\ud558\ub97c 55% \ub2a6\ucd94\ub294 \ud6a8\uacfc\ub97c \ubcf4\uc5ec, \ud6c4\uc18d \ud30c\uc774\ud504\ub77c\uc778 \uacbd\uc7c1\uc790\ub4e4\uc5d0\uac8c \ub354 \ud070 \uc9c0\uc18d\uc131 \ub610\ub294 \ub2e8\uc77c \ud22c\uc5ec \ud3b8\uc758\uc131\uc744 \uc785\uc99d\ud558\ub3c4\ub85d \uc694\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. Nrf2 \uacbd\ub85c\uc758 \uc720\ud6a8\uc131 \uac80\uc99d\uc740 \ucc28\uc138\ub300 \ud56d\uc0b0\ud654\uc81c\uc5d0 \ub300\ud55c \ud22c\uc790\ub97c \ucd09\uc9c4\ud588\uc73c\uba70, \uc218\uc815\ub41c \ud3c9\uac00 \ucc99\ub3c4 \uc885\uc810\uc740 \uc784\uc0c1 \uc2dc\ud5d8 \uc124\uacc4\ub97c \uac04\uc18c\ud654\ud558\ub294 \ub370 \uae30\uc5ec\ud588\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc720\uc804\uc790 \uce58\ub8cc\uc81c R&#038;D \uac00\uc18d\ud654: \uae30\uc5c5\ub4e4\uc740 \uc720\uc804\uc801 \uc6d0\uc778\uc778 \ud504\ub77c\ud0c1\uc2e0(frataxin) \ubcf5\uc6d0\uc744 \ubaa9\ud45c\ub85c \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. Lexeo\uc758 LX2006\uc740 \uc2ec\uadfc\ubcd1\uc99d \ud658\uc790\uc5d0\uc11c 12\uac1c\uc6d4 \ub9cc\uc5d0 \uc88c\uc2ec\uc2e4 \uc9c8\ub7c9 \uc9c0\uc218\ub97c 11.4% \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. Voyager\ub294 Neurocrine\uacfc\uc758 \ud611\ub825\uc744 \ud1b5\ud574 \uc0c8\ub85c\uc6b4 \ucea1\uc2dc\ub4dc\uc640 \uac15\ub825\ud55c \ucc99\uc218 \uce5c\ud654\uc131\uc744 \uacb0\ud569\ud55c \ud6c4\ubcf4 \ubb3c\uc9c8\uc744 \uc120\uc815\ud558\uace0 2025\ub144 \uccab \uc778\uccb4 \ud22c\uc5ec\ub97c \uc2dc\uc791\ud560 \uacc4\ud68d\uc785\ub2c8\ub2e4. \uc0dd\uc0b0 \ub2a5\ub825 \ubd80\uc871\uc740 Novartis\uc758 \ucf5c\ub85c\ub77c\ub3c4 \uc2dc\uc124\uc774\ub098 Roche\uc758 \ub3c5\uc77c \uc13c\ud130\uc640 \uac19\uc740 \uc804\uc6a9 \uacf5\uc7a5 \uac74\uc124\uc744 \ucd09\uc9c4\ud558\uace0 \uc788\uc9c0\ub9cc, \ubca1\ud130 \ubd80\uc871\uc740 \uc5ec\uc804\ud788 \uc77c\ubd80 \uc784\uc0c1 \uc2dc\ud5d8\uc744 \uc9c0\uc5f0\uc2dc\ud0a4\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \ud658\uc790 \ub4f1\ub85d \ud655\ub300 \ubc0f \uc870\uae30 \uc9c4\ub2e8: \uad6d\uacbd\uc744 \ub118\ub294 \ub370\uc774\ud130 \ub124\ud2b8\uc6cc\ud06c\ub294 \uc790\uc5f0 \uacbd\uacfc \uace1\uc120\uc744 \uac1c\uc120\ud558\uc5ec \uc2a4\ud3f0\uc11c\ub4e4\uc774 \ub354 \uc801\uc740 \ud53c\ud5d8\uc790\uc640 \uc9e7\uc740 \uae30\uac04\uc73c\ub85c \uc784\uc0c1 \uc2dc\ud5d8\uc744 \uc9c4\ud589\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \ubbf8\uad6d FA Identified \ud504\ub85c\uadf8\ub7a8\uc740 16\uc138 \uc774\uc0c1 \uac1c\uc778\uc5d0\uac8c \ubb34\ub8cc \uc720\uc804\uc790 \uac80\uc0ac\ub97c \uc9c0\uc6d0\ud558\uc5ec \ud655\uc9c4\uc728\uc744 \ub192\uc774\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc0bc\uc911 \uc0ac\uc911\uadf9\uc790 \uc9c8\ub7c9 \ubd84\uc11d\ubc95\uc740 \uae30\uc874 \ubd84\uc11d\ubc95\uc774 \ub193\uce58\ub358 \ubcf5\ud569 \uc774\ud615\uc811\ud569\uccb4\ub97c \uc815\ud655\ud788 \ucc3e\uc544\ub0b4\uc5b4 \ubcf4\uc778\uc790 \uac80\ucd9c\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uad6d\ubc29\ubd80\uc758 \uc9c0\uc6d0\uae08\uc740 GAA \ubc18\ubcf5 \uae38\uc774 \ub2e8\ucd95\uacfc \uad00\ub828\ub41c \uacbd\ubbf8\ud55c \ud45c\ud604\ud615\uc744 \ubc1d\ud788\ub294 \uc720\uc804\uccb4 \uc5f0\uad6c\ub97c \uac00\ub2a5\ud558\uac8c \ud558\uc5ec \ubbf8\ub798\uc758 \uacc4\uce35\ud654\ub41c \uc758\ud559 \uae30\ud68c\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uace0\ud574\uc0c1\ub3c4 MRI \ubc0f DTI \ubc14\uc774\uc624\ub9c8\ucee4\ub294 1\ub144 \uc774\ub0b4\uc5d0 \uc9c8\ubcd1 \uc9c4\ud589\uc744 \uac10\uc9c0\ud558\uc5ec \ucd08\uae30 \ub2e8\uacc4 \ud504\ub85c\uadf8\ub7a8\uc758 \ubbfc\uac10\ud55c \uc885\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ub3c4\uad6c\ub4e4\uc740 \uce58\ub8cc \uac00\ub2a5\ud55c \uc778\uad6c\ub97c \ud655\ub300\ud558\uc5ec \uc2dc\uc7a5\uc758 \uafb8\uc900\ud55c \uc131\uc7a5\uc744 \ub4b7\ubc1b\uce68\ud569\ub2c8\ub2e4.<br \/>\n*   \uc2e0\uc0dd\uc544 \uc120\ubcc4 \uac80\uc0ac \ud328\ub110 \ud655\uc7a5: \uce98\ub9ac\ud3ec\ub2c8\uc544\uc640 \ub274\uc695\uacfc \uac19\uc740 \uc8fc\ub4e4\uc740 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d(SMA)\uc758 \uc131\uacf5 \uc0ac\ub840\uc5d0 \uc601\uac10\uc744 \ubc1b\uc544 \ud504\ub77c\ud0c1\uc2e0 \uc720\uc804\uc790 \uac80\uc0ac\ub97c \uc77c\uc0c1\uc801\uc778 \uc120\ubcc4 \uac80\uc0ac\uc5d0 \ucd94\uac00\ud558\ub294 \ubc29\uc548\uc744 \uac80\ud1a0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc870\uae30 \uc2dd\ubcc4\uc740 \uce58\ub8cc \uc2dc\uae30\ub97c \uc720\uc544\uae30\ub85c \uc55e\ub2f9\uaca8 \uc2e0\uacbd \uac00\uc18c\uc131\uc774 \uac00\uc7a5 \ub192\uc740 \uc2dc\uae30\uc5d0 \ud3c9\uc0dd\uc758 \uc774\uc810\uc744 \ud655\uace0\ud788 \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uad6c\ud604 \ube44\uc6a9\uc740 \uc5ec\uc804\ud788 \uc7a5\uc560\ubb3c\uc774\uc9c0\ub9cc, \uacf5\uc911 \ubcf4\uac74 \ubaa8\ub378\uc740 \uc870\uae30 \uc720\uc804\uc790 \uce58\ub8cc \uac1c\uc785\uc774 \uc7a5\uae30\uc801\uc778 \uc0ac\ud68c \ubcf5\uc9c0 \uc9c0\ucd9c\uc744 \uc608\ubc29\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n<p>\uc2dc\uc7a5 \uc131\uc7a5 \uc5b5\uc81c \uc694\uc778 (Restraints):<\/p>\n<p>*   \uc81c\ud55c\uc801\uc778 \ud658\uc790 \ud480\ub85c \uc778\ud55c ROI \uc81c\uc57d: \uc804 \uc138\uacc4\uc801\uc73c\ub85c \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \ud658\uc790\ub294 \uc57d 25,000\uba85\uc5d0 \ubd88\uacfc\ud558\uba70, \ubc31\uc778 \uc778\uad6c\uc5d0\uc11c\ub294 20,000\uba85\ub2f9 1\uba85\uc5d0\uc11c 50,000\uba85\ub2f9 1\uba85\uc758 \uc720\ubcd1\ub960\uc744 \ubcf4\uc785\ub2c8\ub2e4. \ucd08\ud76c\uadc0 \uc9c8\ud658\uc758 \uacbd\uc81c\uc131\uc740 \uc5f0\uac04 30\ub9cc \ub2ec\ub7ec \uc774\uc0c1\uc758 \ub192\uc740 \uc57d\uac00\ub97c \ucd08\ub798\ud558\uc5ec \uace0\uc18c\ub4dd \uad6d\uac00\uc5d0\uc11c\ub3c4 \uc9c0\ubd88\uc790\uc758 \ubc18\ubc1c\uc744 \ubd88\ub7ec\uc77c\uc73c\ud0b5\ub2c8\ub2e4. \ud658\uc790 \ubaa8\uc9d1\uc5d0 \uc218\ub144\uc774 \uac78\ub9b4 \uc218 \uc788\uc73c\uba70, \ub2e4\uad6d\uc801 \uc784\uc0c1 \uc2dc\ud5d8\uc740 \uc911\ubcf5\ub418\ub294 \uaddc\uc81c \uc81c\ucd9c\ub85c \uc778\ud574 \ube44\uc6a9\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.<br \/>\n*   \ub192\uc740 \uce58\ub8cc \ube44\uc6a9 \ubc0f \ubcf4\ud5d8 \uc0c1\ud658 \uc7a5\ubcbd: \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uc758 \uc18c\ub9e4 \uac00\uaca9\uc740 \uc5f0\uac04 \uc57d 37\ub9cc \ub2ec\ub7ec\uc5d0 \ub2ec\ud558\uba70, \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc804 \uc2b9\uc778\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uc720\uc804\uc790 \uce58\ub8cc\uc81c \ud6c4\ubcf4 \ubb3c\uc9c8\uc740 1\ud68c \ud22c\uc5ec\ub2f9 100\ub9cc \ub2ec\ub7ec\ub97c \ucd08\uacfc\ud558\ub294 \ucd9c\uc2dc \uac00\uaca9\uc774 \uc608\uc0c1\ub418\uc5b4 \ubcf4\uac74 \uae30\uc220 \ud3c9\uac00 \ubaa8\ub378\uc5d0 \ubd80\ub2f4\uc744 \uc90d\ub2c8\ub2e4. \uc720\ub7fd\uc758 \ubd84\uc0b0\ub41c \ubcf4\ud5d8 \uc0c1\ud658 \uc2dc\uc2a4\ud15c\uc740 \ub3c5\uc77c\uc5d0\uc11c\ub294 \uba87 \ub2ec, \uc2a4\ud398\uc778\uc5d0\uc11c\ub294 \uba87 \ub144\uae4c\uc9c0 \uc218\uc775 \ubc1c\uc0dd \uc2dc\uae30\uac00 \ub2e4\uc591\ud558\uac8c \ub098\ud0c0\ub098\ub294 \ubcf5\uc7a1\uc131\uc744 \uc57c\uae30\ud569\ub2c8\ub2e4. \uc2e0\ud765 \uc2dc\uc7a5\uc740 \ucd08\ud76c\uadc0 \uc9c8\ud658 \uce58\ub8cc\uc81c\uc5d0 \ub300\ud55c \uc790\uae08 \uc870\ub2ec\uc5d0 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc5b4 \uae00\ub85c\ubc8c \uc2dc\uc7a5 \uce68\ud22c\ub97c \uc81c\ud55c\ud569\ub2c8\ub2e4.<br \/>\n*   \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub3c5\uc131 \uc6b0\ub824: \ud2b9\uc815 \uc57d\ubb3c \ud6c4\ubcf4 \ubb3c\uc9c8\uacfc \uad00\ub828\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub3c5\uc131 \uc6b0\ub824\ub294 \uc5c4\uaca9\ud55c \uc548\uc804 \uaddc\uc81c\ub97c \uac00\uc9c4 \uc9c0\uc5ed\uc5d0\uc11c \uac1c\ubc1c \ubc0f \uc2b9\uc778\uc5d0 \ub300\ud55c \ucd94\uac00\uc801\uc778 \uc870\uc0ac\ub97c \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc81c\ud55c\uc801\uc778 \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130 \uc0dd\uc0b0 \ub2a5\ub825: \uc720\uc804\uc790 \uce58\ub8cc\uc81c\uc758 \ud575\uc2ec \uad6c\uc131 \uc694\uc18c\uc778 \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130\uc758 \uc0dd\uc0b0 \ub2a5\ub825 \ubd80\uc871\uc740 \uc804 \uc138\uacc4\uc801\uc73c\ub85c, \ud2b9\ud788 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc5d0\uc11c \ubcd1\ubaa9 \ud604\uc0c1\uc744 \uc77c\uc73c\ucf1c \uc784\uc0c1 \uc2dc\ud5d8 \ubc0f \uc0c1\uc5c5\uc801 \ucd9c\uc2dc\ub97c \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc138\uadf8\uba3c\ud2b8 \ubd84\uc11d<\/p>\n<p>*   \uce58\ub8cc \uc720\ud615\ubcc4: \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\uc81c\uac00 \uc131\uc7a5\uc744 \uacac\uc778: 2024\ub144 \ub9e4\ucd9c\uc758 90.43%\ub97c \uc9c8\ubcd1 \uc870\uc808 \uce58\ub8cc\uc81c\uac00 \ucc28\uc9c0\ud588\uc73c\uba70, \uc774\ub294 \ubbf8\uad6d\uacfc \uc720\ub7fd \uc804\uc5ed\uc5d0\uc11c SKYCLARYS\uc758 \ucc44\ud0dd\uc5d0 \ud798\uc785\uc740 \uacb0\uacfc\uc785\ub2c8\ub2e4. \uc720\uc804\uc790 \uce58\ub8cc\uc81c \uc2dc\uc7a5 \uaddc\ubaa8\ub294 LX2006 \ubc0f Voyager\uc758 \ud6c4\ubcf4 \ubb3c\uc9c8\uacfc \uac19\uc740 \ud504\ub85c\uadf8\ub7a8\uc758 \ubc1c\uc804\uc73c\ub85c \uc5f0\ud3c9\uade0 11.23%\uc758 \uae09\uc99d\uc774 \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n*   \uc57d\ubb3c \ubd84\ub958\ubcc4: \ud56d\uc0b0\ud654\uc81c\uac00 \uc120\ub450 \uc720\uc9c0, \uc548\uc815\uc81c \uac00\uc18d\ud654: 2024\ub144 \ud56d\uc0b0\ud654\uc81c\/Nrf2 \ud65c\uc131\uc81c\uac00 \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uc758 \uc131\uacf5\uc801\uc778 \ucd9c\uc2dc \ub355\ubd84\uc5d0 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 88.56%\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc548\uc815\uc81c\ub294 \ud504\ub77c\ud0c1\uc2e0 \uc218\uce58\uc758 \uc6a9\ub7c9 \uc758\uc874\uc801 \uc99d\uac00\ub97c \ubcf4\uc5ec\uc900 \ub188\ub77c\ubcf4\ud478\uc2a4\ud504(nomlabofusp)\uc758 2\uc0c1 \ub370\uc774\ud130\uc5d0 \ud798\uc785\uc5b4 \uc5f0\ud3c9\uade0 10.52%\uc758 \uc131\uc7a5\ub960\uc744 \uae30\ub85d\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \ud22c\uc5ec \uacbd\ub85c\ubcc4: \uacbd\uad6c \ud22c\uc5ec\uc758 \uc9c0\ubc30\ub825, \ud45c\uc801 \uc804\ub2ec\uc758 \ud544\uc694\uc131: 2024\ub144 \ub9e4\ucd9c\uc758 89.37%\ub97c \uacbd\uad6c\uc6a9 \uc81c\ud488\uc774 \ucc28\uc9c0\ud558\uc5ec \ubcf5\uc57d \uc21c\uc751\ub3c4\ub97c \ud655\ubcf4\ud558\uace0 \uad11\ubc94\uc704\ud55c \ucc98\ubc29\uc744 \uc6a9\uc774\ud558\uac8c \ud588\uc2b5\ub2c8\ub2e4. \uc720\uc804\uc790 \uce58\ub8cc\uc81c\uac00 \uc18c\ub1cc \ub610\ub294 \ucc99\uc218\uc5d0 \uc9c1\uc811 \uc811\uadfc\ud574\uc57c \ud568\uc5d0 \ub530\ub77c \uc218\ub9c9\uac15\ub0b4 \ud22c\uc5ec\ub294 \uc5f0\ud3c9\uade0 9.01%\ub85c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc5f0\ub839 \uadf8\ub8f9\ubcc4: \uc131\uc778 \uce58\ub8cc\uc5d0\uc11c \uc18c\uc544 \uac1c\uc785\uc73c\ub85c \uc804\ud658: 2024\ub144 \ub9e4\ucd9c\uc758 61.22%\ub294 18-40\uc138 \uc131\uc778 \ud658\uc790\uc5d0\uc11c \ubc1c\uc0dd\ud588\uc2b5\ub2c8\ub2e4. \uc18c\uc544 \ud658\uc790 \uce58\ub8cc\ub294 \ubc14\ud2f0\ud034\ub17c\uc774 \uc5b4\ub9b0\uc774\uc6a9 FDA \uc2b9\uc778\uc744 \ucd94\uc9c4\ud558\uace0, \uae00\ub85c\ubc8c 3\uc0c1 \uc5f0\uad6c\uc778 BRAVE\uac00 2\uc138 \uc544\ub3d9\uc5d0\uac8c \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uc744 \ud3c9\uac00\ud568\uc5d0 \ub530\ub77c 2030\ub144\uae4c\uc9c0 \uc5f0\ud3c9\uade0 9.87%\uc758 \uc131\uc7a5\ub960\uc744 \ubcf4\uc77c \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc774\ub294 \uc870\uae30 \uac1c\uc785\uc758 \uc911\uc694\uc131\uc5d0 \ub300\ud55c \uc778\uc2dd\uc774 \ub192\uc544\uc9c0\uace0 \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc774 \uac1c\ubc1c\ub428\uc5d0 \ub530\ub978 \uac83\uc785\ub2c8\ub2e4.<\/p>\n<p>*   \ucd5c\uc885 \uc0ac\uc6a9\uc790\ubcc4: \ubcd1\uc6d0 \ubc0f \ud074\ub9ac\ub2c9\uc774 \uc2dc\uc7a5\uc744 \uc8fc\ub3c4: 2024\ub144 \uc2dc\uc7a5\uc758 65.43%\ub97c \ubcd1\uc6d0 \ubc0f \ud074\ub9ac\ub2c9\uc774 \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc804\ubb38 \uc758\ub8cc \uc2dc\uc124\uc5d0\uc11c \uc9c4\ub2e8 \ubc0f \uce58\ub8cc\uac00 \uc774\ub8e8\uc5b4\uc9c0\ub294 \uacbd\uc6b0\uac00 \ub9ce\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uc5f0\uad6c \uae30\uad00\uc740 \uc2e0\uc57d \uac1c\ubc1c \ubc0f \uc784\uc0c1 \uc2dc\ud5d8\uc744 \ud1b5\ud574 \uc2dc\uc7a5 \uc131\uc7a5\uc5d0 \uae30\uc5ec\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc9c0\uc5ed \ubd84\uc11d: \ubd81\ubbf8\uac00 \uc2dc\uc7a5\uc744 \uc8fc\ub3c4, \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc758 \uc131\uc7a5 \uc7a0\uc7ac\ub825<\/p>\n<p>*   \ubd81\ubbf8: 2024\ub144 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5\uc758 42.15%\ub97c \ucc28\uc9c0\ud558\uba70 \uc9c0\ubc30\uc801\uc778 \uc704\uce58\ub97c \uc720\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub192\uc740 \uc9c8\ubcd1 \uc720\ubcd1\ub960, \uc120\uc9c4 \uc758\ub8cc \uc778\ud504\ub77c, \uc8fc\uc694 \uc81c\uc57d \ud68c\uc0ac\uc758 \uc874\uc7ac, \uadf8\ub9ac\uace0 \uc720\ub9ac\ud55c \uc0c1\ud658 \uc815\ucc45 \ub355\ubd84\uc785\ub2c8\ub2e4. \ud2b9\ud788 \ubbf8\uad6d\uc740 \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uc758 \uc131\uacf5\uc801\uc778 \ucd9c\uc2dc\uc640 \uac15\ub825\ud55c R&#038;D \ud65c\ub3d9\uc73c\ub85c \uc2dc\uc7a5\uc744 \uc8fc\ub3c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc720\ub7fd: 2024\ub144 \uc2dc\uc7a5 \uc810\uc720\uc728\uc758 30.28%\ub97c \ucc28\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \uc720\ub7fd\uc740 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d\uc5d0 \ub300\ud55c \uc778\uc2dd\uc774 \ub192\uace0, \uc815\ubd80 \uc9c0\uc6d0 \ud504\ub85c\uadf8\ub7a8 \ubc0f \uc5f0\uad6c \uc790\uae08 \uc9c0\uc6d0\uc774 \ud65c\ubc1c\ud558\uba70, \uc5ec\ub7ec \uc784\uc0c1 \uc2dc\ud5d8\uc774 \uc9c4\ud589 \uc911\uc785\ub2c8\ub2e4. \ub3c5\uc77c, \ud504\ub791\uc2a4, \uc601\uad6d\uc774 \uc8fc\uc694 \uc2dc\uc7a5\uc785\ub2c8\ub2e4.<br \/>\n*   \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591: 2024\ub144 \uc5f0\ud3c9\uade0 11.25%\ub85c \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud558\ub294 \uc9c0\uc5ed\uc73c\ub85c \ubd80\uc0c1\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc758\ub8cc \uc9c0\ucd9c \uc99d\uac00, \uc758\ub8cc \uc778\ud504\ub77c \uac1c\uc120, \uc9c8\ubcd1 \uc9c4\ub2e8\uc728 \ud5a5\uc0c1, \uadf8\ub9ac\uace0 \uc8fc\uc694 \uc81c\uc57d \ud68c\uc0ac\ub4e4\uc758 \uc2dc\uc7a5 \uc9c4\ucd9c \ub178\ub825\uc5d0 \ud798\uc785\uc740 \uac83\uc785\ub2c8\ub2e4. \ud2b9\ud788 \uc77c\ubcf8, \uc911\uad6d, \uc778\ub3c4\uac00 \uc774 \uc9c0\uc5ed\uc758 \uc131\uc7a5\uc744 \uc8fc\ub3c4\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<br \/>\n*   \ub77c\ud2f4 \uc544\uba54\ub9ac\uce74, \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74: \uc774 \uc9c0\uc5ed\ub4e4\uc740 \ud604\uc7ac \uc2dc\uc7a5 \uc810\uc720\uc728\uc740 \ub0ae\uc9c0\ub9cc, \uc758\ub8cc \uc811\uadfc\uc131 \uac1c\uc120\uacfc \uc9c8\ubcd1 \uc778\uc2dd \uc99d\ub300\ub85c \uc778\ud574 \ud5a5\ud6c4 \uc0c1\ub2f9\ud55c \uc131\uc7a5 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uacbd\uc7c1 \ud658\uacbd: \uc8fc\uc694 \uae30\uc5c5 \ubc0f \uc804\ub7b5\uc801 \uc774\ub2c8\uc154\ud2f0\ube0c<\/p>\n<p>\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5\uc740 \uba87\uba87 \uc8fc\uc694 \uae30\uc5c5\ub4e4\uc774 \uc9c0\ubc30\ud558\uace0 \uc788\uc73c\uba70, \uc774\ub4e4\uc740 \uc2e0\uc57d \uac1c\ubc1c, \uc804\ub7b5\uc801 \uc81c\ud734, \uc778\uc218 \ud569\ubcd1\uc744 \ud1b5\ud574 \uc2dc\uc7a5 \uc810\uc720\uc728\uc744 \ud655\ub300\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc8fc\uc694 \uc2dc\uc7a5 \ucc38\uc5ec\uc790\ub294 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.<\/p>\n<p>*   \ub9ac\ud0c0\ud30c\ub9c8(Reata Pharmaceuticals, Inc.)<br \/>\n*   PTC \ud14c\ub77c\ud4e8\ud2f1\uc2a4(PTC Therapeutics)<br \/>\n*   \ubc14\uc774\uc624\ub9c8\ub9b0 \ud30c\ub9c8\uc288\ud2f0\uceec(BioMarin Pharmaceutical Inc.)<br \/>\n*   \uc0b0\ub4dc\ub77c \ud14c\ub77c\ud4e8\ud2f1\uc2a4(Santhera Pharmaceuticals)<br \/>\n*   \uc544\ud0c0\ub77c \ubc14\uc774\uc624\ud14c\ub77c\ud4e8\ud2f1\uc2a4(Atara Biotherapeutics)<br \/>\n*   \uc544\ubca0\uc624 \ud30c\ub9c8\uc288\ud2f0\uceec\uc2a4(Aveo Pharmaceuticals)<br \/>\n*   \ud504\ub85d\uc2dc\ub9c8 \ud14c\ub77c\ud4e8\ud2f1\uc2a4(Proxima Therapeutics)<br \/>\n*   \uc544\uce74\ub514\uc544 \ud30c\ub9c8\uc288\ud2f0\uceec\uc2a4(Acadia Pharmaceuticals)<br \/>\n*   \ubc14\uc774\uc624\uc820(Biogen)<br \/>\n*   \ub178\ubc14\ud2f0\uc2a4(Novartis AG)<\/p>\n<p>\uc774\ub4e4 \uae30\uc5c5\uc740 \uc5f0\uad6c \uac1c\ubc1c\uc5d0 \ub9c9\ub300\ud55c \ud22c\uc790\ub97c \ud558\uace0 \uc788\uc73c\uba70, \ud2b9\ud788 \uc720\uc804\uc790 \uce58\ub8cc, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uac1c\uc120\uc81c, \ud56d\uc0b0\ud654\uc81c \ub4f1 \ud601\uc2e0\uc801\uc778 \uce58\ub8cc\ubc95 \uac1c\ubc1c\uc5d0 \uc9d1\uc911\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ub9ac\ud0c0\ud30c\ub9c8\uc758 \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uc740 \uc2dc\uc7a5\uc5d0\uc11c \uc911\uc694\ud55c \uc704\uce58\ub97c \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70, \ub2e4\ub978 \uae30\uc5c5\ub4e4\ub3c4 \ud6c4\uc18d \ud30c\uc774\ud504\ub77c\uc778\uc744 \uac15\ud654\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc804\ub7b5\uc801 \uc81c\ud734\uc640 \ud611\ub825\uc740 \uc2e0\uc57d \uac1c\ubc1c\uc758 \uc704\ud5d8\uc744 \ubd84\uc0b0\ud558\uace0 \uc2dc\uc7a5 \uc811\uadfc\uc131\uc744 \ub192\uc774\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.<\/p>\n<p>\uc2dc\uc7a5 \ub3d9\ud5a5 \ubc0f \uae30\ud68c<\/p>\n<p>*   \uc720\uc804\uc790 \uce58\ub8cc\uc758 \ubd80\uc0c1: \ud504\ub77c\ud0c1\uc2e0 \uc720\uc804\uc790 \uacb0\ud568\uc774 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d\uc758 \uadfc\ubcf8 \uc6d0\uc778\uc778 \ub9cc\ud07c, \uc720\uc804\uc790 \uce58\ub8cc\ub294 \uc7a5\uae30\uc801\uc778 \uce58\ub8cc \uac00\ub2a5\uc131\uc744 \uc81c\uacf5\ud558\uba70 \uac00\uc7a5 \uc720\ub9dd\ud55c \ubd84\uc57c \uc911 \ud558\ub098\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4. \uc5ec\ub7ec \uae30\uc5c5\ub4e4\uc774 \uc720\uc804\uc790 \ub300\uccb4 \ubc0f \uc720\uc804\uc790 \ud3b8\uc9d1 \uae30\uc220\uc744 \uc5f0\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \ubc14\uc774\uc624\ub9c8\ucee4 \uac1c\ubc1c: \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ubaa8\ub2c8\ud130\ub9c1\ud558\uace0 \uce58\ub8cc \ud6a8\uacfc\ub97c \ud3c9\uac00\ud560 \uc218 \uc788\ub294 \ubc14\uc774\uc624\ub9c8\ucee4\uc758 \uac1c\ubc1c\uc740 \uc784\uc0c1 \uc2dc\ud5d8\uc758 \ud6a8\uc728\uc131\uc744 \ub192\uc774\uace0 \ud658\uc790 \ub9de\ucda4\ud615 \uce58\ub8cc\ub97c \uac00\ub2a5\ud558\uac8c \ud560 \uac83\uc785\ub2c8\ub2e4.<br \/>\n*   \ud76c\uadc0 \uc758\uc57d\ud488 \uc9c0\uc815 \ubc0f \uc778\uc13c\ud2f0\ube0c: \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d\uc740 \ud76c\uadc0 \uc9c8\ud658\uc73c\ub85c \ubd84\ub958\ub418\uc5b4, \uac1c\ubc1c \uae30\uc5c5\ub4e4\uc740 \ud76c\uadc0 \uc758\uc57d\ud488 \uc9c0\uc815\uc5d0 \ub530\ub978 \uc138\uae08 \ud61c\ud0dd, \uc2dc\uc7a5 \ub3c5\uc810\uad8c \uc5f0\uc7a5 \ub4f1\uc758 \uc778\uc13c\ud2f0\ube0c\ub97c \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 R&#038;D \ud22c\uc790\ub97c \ucd09\uc9c4\ud558\ub294 \uc694\uc778\uc785\ub2c8\ub2e4.<br \/>\n*   \ud658\uc790 \uc9c0\uc6d0 \ubc0f \uc639\ud638 \ub2e8\uccb4\uc758 \uc5ed\ud560: \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \ud658\uc790 \ubc0f \uac00\uc871 \uc9c0\uc6d0 \ub2e8\uccb4\ub4e4\uc740 \uc9c8\ubcd1 \uc778\uc2dd \uc81c\uace0, \uc5f0\uad6c \uc790\uae08 \ubaa8\uae08, \uc784\uc0c1 \uc2dc\ud5d8 \ucc38\uc5ec \ub3c5\ub824 \ub4f1 \uc2dc\uc7a5 \uc131\uc7a5\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\ub3c4\uc804 \uacfc\uc81c \ubc0f \uc704\ud611 \uc694\uc778<\/p>\n<p>*   \ub192\uc740 \uce58\ub8cc \ube44\uc6a9: \ud601\uc2e0\uc801\uc778 \uce58\ub8cc\ubc95, \ud2b9\ud788 \uc720\uc804\uc790 \uce58\ub8cc\ub294 \uac1c\ubc1c \ubc0f \uc0dd\uc0b0 \ube44\uc6a9\uc774 \ub192\uc544 \ud658\uc790\uc640 \uc758\ub8cc \uc2dc\uc2a4\ud15c\uc5d0 \uc0c1\ub2f9\ud55c \uc7ac\uc815\uc801 \ubd80\ub2f4\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc9c4\ub2e8 \uc9c0\uc5f0: \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d\uc740 \uc9c4\ub2e8\uc774 \uc5b4\ub835\uace0 \uc2dc\uac04\uc774 \uc624\ub798 \uac78\ub9ac\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc544, \uc870\uae30 \uac1c\uc785\uc758 \uae30\ud68c\ub97c \ub193\uce58\uac8c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uc784\uc0c1 \uc2dc\ud5d8\uc758 \ubcf5\uc7a1\uc131: \ud76c\uadc0 \uc9c8\ud658\uc758 \ud2b9\uc131\uc0c1 \ud658\uc790 \ubaa8\uc9d1\uc774 \uc5b4\ub835\uace0, \uc9c8\ubcd1\uc758 \uc774\uc9c8\uc131\uc73c\ub85c \uc778\ud574 \uc784\uc0c1 \uc2dc\ud5d8 \uc124\uacc4 \ubc0f \uacb0\uacfc \ud574\uc11d\uc774 \ubcf5\uc7a1\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<br \/>\n*   \uce58\ub8cc\ubc95\uc758 \uc81c\ud55c\ub41c \ud6a8\ub2a5: \ud604\uc7ac \uc2b9\uc778\ub41c \uce58\ub8cc\ubc95\ub4e4\uc740 \uc99d\uc0c1 \uc644\ud654\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uace0 \uc788\uc73c\uba70, \uc9c8\ubcd1\uc758 \uc9c4\ud589\uc744 \uc644\uc804\ud788 \uba48\ucd94\uac70\ub098 \uc5ed\uc804\uc2dc\ud0a4\ub294 \ub370\ub294 \ud55c\uacc4\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uacb0\ub860<\/p>\n<p>\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5\uc740 \uc624\ub9c8\ubca8\ub85d\uc194\ub860\uacfc \uac19\uc740 \ud601\uc2e0\uc801\uc778 \uce58\ub8cc\uc81c\uc758 \ucd9c\uc2dc\uc640 \uc720\uc804\uc790 \uce58\ub8cc \uc5f0\uad6c\uc758 \uc9c4\uc804\uc73c\ub85c \uc778\ud574 \uc0c1\ub2f9\ud55c \uc131\uc7a5\uc138\ub97c \ubcf4\uc774\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubd81\ubbf8\uac00 \uc2dc\uc7a5\uc744 \uc8fc\ub3c4\ud558\uace0 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc774 \uac00\uc7a5 \ube60\ub974\uac8c \uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uac00\uc6b4\ub370, \uc8fc\uc694 \uc81c\uc57d \ud68c\uc0ac\ub4e4\uc740 R&#038;D \ud22c\uc790\uc640 \uc804\ub7b5\uc801 \uc81c\ud734\ub97c \ud1b5\ud574 \uc2dc\uc7a5 \uacbd\uc7c1\ub825\uc744 \uac15\ud654\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub192\uc740 \uce58\ub8cc \ube44\uc6a9\uacfc \uc9c4\ub2e8 \uc9c0\uc5f0 \ub4f1\uc758 \ub3c4\uc804 \uacfc\uc81c\uac00 \ub0a8\uc544 \uc788\uc9c0\ub9cc, \uc870\uae30 \uc9c4\ub2e8 \uac1c\uc120, \ubc14\uc774\uc624\ub9c8\ucee4 \uac1c\ubc1c, \uadf8\ub9ac\uace0 \uc720\uc804\uc790 \uce58\ub8cc\uc758 \uc0c1\uc6a9\ud654\ub294 \ud5a5\ud6c4 \uc2dc\uc7a5 \uc131\uc7a5\uc744 \ub354\uc6b1 \uac00\uc18d\ud654\ud560 \uc8fc\uc694 \uae30\ud68c\uac00 \ub420 \uac83\uc785\ub2c8\ub2e4.<\/p>\n<p>\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d(Friedreich&#8217;s Ataxia) \uc2dc\uc7a5 \ubcf4\uace0\uc11c \uc694\uc57d<\/p>\n<p>\ubcf8 \ubcf4\uace0\uc11c\ub294 \uc720\uc804\uc131 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc778 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d(FA) \uc2dc\uc7a5\uc5d0 \ub300\ud55c \ud3ec\uad04\uc801\uc778 \ubd84\uc11d\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. FA\ub294 FXN \uc720\uc804\uc790 \ubcc0\uc774\ub85c \uc778\ud574 \ud504\ub77c\ud0c1\uc2e0 \ub2e8\ubc31\uc9c8 \uc0dd\uc0b0\uc774 \uac10\uc18c\ud558\uc5ec \ud611\uc751\ub825 \uc800\ud558, \uadfc\ub825 \uc57d\ud654, \ubcf4\ud589 \uc7a5\uc560 \ub4f1\uc744 \uc720\ubc1c\ud558\uba70, \ud604\uc7ac \uce58\ub8cc\ub294 \uc8fc\ub85c \uc99d\uc0c1 \uad00\ub9ac\uc5d0 \uc911\uc810\uc744 \ub450\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>1. \uc2dc\uc7a5 \uac1c\uc694 \ubc0f \uc804\ub9dd<br \/>\n\ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5\uc740 2030\ub144\uae4c\uc9c0 20\uc5b5 7\ucc9c\ub9cc \ub2ec\ub7ec \uaddc\ubaa8\uc5d0 \uc774\ub97c \uac83\uc73c\ub85c \uc804\ub9dd\ub429\ub2c8\ub2e4. \ud2b9\ud788 \uc720\uc804\uc790 \uce58\ub8cc\ubc95\uc740 2025\ub144\ubd80\ud130 2030\ub144\uae4c\uc9c0 \uc5f0\ud3c9\uade0 11.23%\uc758 \uac00\uc7a5 \ube60\ub978 \uc131\uc7a5\ub960\uc744 \ubcf4\uc77c \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \ud604\uc7ac \uc2dc\uc7a5\uc5d0\uc11c\ub294 \uc624\ub9c8\ubca8\ub85d\uc194\ub860(Omaveloxolone) \ucd9c\uc2dc\uc758 \uc601\ud5a5\uc73c\ub85c \ud56d\uc0b0\ud654\uc81c\/Nrf2 \ud65c\uc131\uc81c(Antioxidant\/Nrf2 Activators)\uac00 2024\ub144 \ub9e4\ucd9c\uc758 88.56%\ub97c \ucc28\uc9c0\ud558\uba70 \uc9c0\ubc30\uc801\uc778 \uc704\uce58\ub97c \uc810\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc9c0\uc5ed\ubcc4\ub85c\ub294 \uc544\uc2dc\uc544-\ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc774 \ud658\uc790 \ub4f1\ub85d \ud655\ub300, \uc2e0\uc0dd\uc544 \uc120\ubcc4 \uac80\uc0ac, \uc911\uad6d \ubc0f \uc77c\ubcf8\uc758 \ud76c\uadc0 \uc9c8\ud658 \uc815\ucc45\uc5d0 \ud798\uc785\uc5b4 \uc5f0\ud3c9\uade0 9.47%\uc758 \uac00\uc7a5 \ub192\uc740 \uc131\uc7a5\ub960\uc744 \uae30\ub85d\ud560 \uac83\uc73c\ub85c \uc608\uce21\ub429\ub2c8\ub2e4.<\/p>\n<p>2. \uc2dc\uc7a5 \ub3d9\uc778<br \/>\n\uc2dc\uc7a5\uc758 \uc131\uc7a5\uc744 \uacac\uc778\ud558\ub294 \uc8fc\uc694 \uc694\uc778\ub4e4\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.<br \/>\n*   \ucd5c\ucd08\uc758 \uc9c8\ubcd1 \uc644\ud654 \uce58\ub8cc\uc81c(\uc624\ub9c8\ubca8\ub85d\uc194\ub860)\uc758 \uaddc\uc81c \uc2b9\uc778<br \/>\n*   \uc720\uc804\uc790 \uce58\ub8cc \uc5f0\uad6c \uac1c\ubc1c \ud22c\uc790 \uc99d\uac00<br \/>\n*   \ud658\uc790 \ub4f1\ub85d \ud655\ub300 \ubc0f \uc870\uae30 \uc9c4\ub2e8 \uac1c\uc120<br \/>\n*   \uc2e0\uc0dd\uc544 \uc120\ubcc4 \uac80\uc0ac \ud328\ub110 \ud655\uc7a5<br \/>\n*   AI \uae30\ubc18 \uc57d\ubb3c \uc7ac\ucc3d\ucd9c \ub178\ub825<br \/>\n*   \ucd08\ud76c\uadc0 \uc9c8\ud658 \uc81c\uc870\uc5d0 \ub300\ud55c \ud76c\uadc0 \uc758\uc57d\ud488 \uc138\uae08 \uc778\uc13c\ud2f0\ube0c<\/p>\n<p>3. \uc2dc\uc7a5 \uc81c\uc57d<br \/>\n\ubc18\uba74, \uc2dc\uc7a5 \uc131\uc7a5\uc744 \uc800\ud574\ud558\ub294 \uc694\uc778\ub4e4\ub3c4 \uc874\uc7ac\ud569\ub2c8\ub2e4.<br \/>\n*   \uc81c\ud55c\uc801\uc778 \ud658\uc790 \ud480\ub85c \uc778\ud55c \ud22c\uc790 \uc218\uc775\ub960(ROI) \uc81c\uc57d<br \/>\n*   \ub192\uc740 \uce58\ub8cc \ube44\uc6a9 \ubc0f \ubcf4\ud5d8 \uc0c1\ud658 \uc7a5\ubcbd<br \/>\n*   \uc720\uc804\uc790 \ubca1\ud130\uc5d0 \ub300\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub3c5\uc131 \uc6b0\ub824<br \/>\n*   \uc81c\ud55c\uc801\uc778 \uae00\ub85c\ubc8c \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130 \uc0dd\uc0b0 \ub2a5\ub825<\/p>\n<p>4. \uc2dc\uc7a5 \uc138\ubd84\ud654<br \/>\n\ubcf8 \ubcf4\uace0\uc11c\ub294 \uc2dc\uc7a5\uc744 \ub2e4\uc591\ud55c \uae30\uc900\uc73c\ub85c \uc138\ubd84\ud654\ud558\uc5ec \ubd84\uc11d\ud569\ub2c8\ub2e4.<br \/>\n*   \uce58\ub8cc \uc720\ud615\ubcc4: \uc9c8\ubcd1 \uc644\ud654 \uce58\ub8cc\uc81c, \uc720\uc804\uc790 \uce58\ub8cc\uc81c, \ub2e8\ubc31\uc9c8 \ub300\uccb4 \uce58\ub8cc\uc81c, RNA \uae30\ubc18 \uce58\ub8cc\uc81c, \uc99d\uc0c1 \uc644\ud654 \uce58\ub8cc\uc81c.<br \/>\n*   \uc57d\ubb3c \ubd84\ub958\ubcc4: \ud56d\uc0b0\ud654\uc81c\/Nrf2 \ud65c\uc131\uc81c, PPAR \uc791\uc6a9\uc81c, \ud504\ub77c\ud0c1\uc2e0 \uc720\uc804\uc790 \ubca1\ud130(AAV, \ub80c\ud2f0\ubc14\uc774\ub7ec\uc2a4), \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc548\uc815\uc81c \ub4f1.<br \/>\n*   \ud22c\uc5ec \uacbd\ub85c\ubcc4: \uacbd\uad6c, \uc815\ub9e5 \uc8fc\uc0ac, \ucc99\uc218\uac15 \ub0b4 \uc8fc\uc0ac, \ud53c\ud558 \uc8fc\uc0ac.<br \/>\n*   \uc5f0\ub839 \uadf8\ub8f9\ubcc4: \uc18c\uc544(18\uc138 \ubbf8\ub9cc), \uc131\uc778(18-40\uc138), \ud6c4\uae30 \ubc1c\ubcd1(40\uc138 \ucd08\uacfc).<br \/>\n*   \uc720\ud1b5 \ucc44\ub110\ubcc4: \ubcd1\uc6d0 \uc57d\uad6d, \uc804\ubb38 \uc57d\uad6d, \uc628\ub77c\uc778 \uc57d\uad6d.<br \/>\n*   \uc9c0\uc5ed\ubcc4: \ubd81\ubbf8(\ubbf8\uad6d, \uce90\ub098\ub2e4, \uba55\uc2dc\ucf54), \uc720\ub7fd(\ub3c5\uc77c, \uc601\uad6d, \ud504\ub791\uc2a4, \uc774\ud0c8\ub9ac\uc544, \uc2a4\ud398\uc778 \ub4f1), \uc544\uc2dc\uc544-\ud0dc\ud3c9\uc591(\uc911\uad6d, \uc77c\ubcf8, \uc778\ub3c4, \ud638\uc8fc, \ud55c\uad6d \ub4f1), \uc911\ub3d9 \ubc0f \uc544\ud504\ub9ac\uce74, \ub0a8\ubbf8.<\/p>\n<p>5. \uacbd\uc7c1 \ud658\uacbd<br \/>\n\ubcf4\uace0\uc11c\ub294 \uc2dc\uc7a5 \uc9d1\uc911\ub3c4, \uc2dc\uc7a5 \uc810\uc720\uc728 \ubd84\uc11d \ubc0f \uc8fc\uc694 \uae30\uc5c5 \ud504\ub85c\ud544\uc744 \ud3ec\ud568\ud55c \uacbd\uc7c1 \ud658\uacbd\uc744 \ub2e4\ub8f9\ub2c8\ub2e4. \uc8fc\uc694 \uae30\uc5c5\uc73c\ub85c\ub294 Agios Pharmaceuticals, Biogen, CRISPR Therapeutics, Novartis, Takeda Pharmaceutical \ub4f1\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>6. \uc2dc\uc7a5 \uae30\ud68c \ubc0f \ubbf8\ub798 \uc804\ub9dd<br \/>\n\ubbf8\ucda9\uc871 \uc218\uc694 \ud3c9\uac00\ub97c \ud1b5\ud574 \uc2dc\uc7a5\uc758 \uc7a0\uc7ac\uc801 \uae30\ud68c\uc640 \ubbf8\ub798 \uc804\ub9dd\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4. \ud2b9\ud788 \uc720\uc804\uc790 \uce58\ub8cc\ubc95\uc758 \ub2e8\uae30 \uacf5\uae09 \uc81c\uc57d\uc740 \uae00\ub85c\ubc8c \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130 \uc81c\uc870 \ub2a5\ub825 \ubc0f \uc6d0\uc790\uc7ac \ubd80\uc871\uc5d0 \uae30\uc778\ud569\ub2c8\ub2e4.<\/p>\n<p>\ubcf8 \ubcf4\uace0\uc11c\ub294 \ud504\ub9ac\ub4dc\ub77c\uc774\ud788 \uc6b4\ub3d9\uc2e4\uc870\uc99d \uc2dc\uc7a5\uc758 \ud604\uc7ac \uc0c1\ud669\uacfc \ubbf8\ub798 \ubc29\ud5a5\uc744 \uc774\ud574\ud558\ub294 \ub370 \uc911\uc694\ud55c \ud1b5\ucc30\ub825\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-42000","post","type-post","status-publish","format-standard","hentry","category-market-reports"],"_links":{"self":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/42000"}],"collection":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/comments?post=42000"}],"version-history":[{"count":0,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/posts\/42000\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/media?parent=42000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/categories?post=42000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.globalresearch.co.kr\/insight\/wp-json\/wp\/v2\/tags?post=42000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}